International Journal of

Cancer and Clinical ResearchISSN: 2378-3419

Archive

 Open Access DOI:10.23937/2378-3419/1/1/1008

HER2 Positive Gastric And Gastroesophageal Adenocarcinoma; An Irish Tertiary Center Experience

Yasir Y Elamin, Shereen Rafee, Mutaz M Nur, Nemer Osman, John V Reynolds, Cian Muldoon and Kenneth J O'Byrne

Article Type: Research Article | First Published: October 29, 2014

Background: Trastuzumab has been approved for patients with human epidermal growth factor receptor 2 (HER2) over expression and gene amplifiation metastatic gastric cancer. Here we present the prevalence of HER2 positive gastric cancer in an Irish population, the use of Trastuzumab in fist line and beyond progression. Methods: The study was conducted in St James’s Hospital, Dublin. A retrospective analysis of the date of patients with HER2 positive gastric cancer over a period of 3 years was c...

 Open Access DOI:10.23937/2378-3419/1/1/1007

Epidemiology and Radiotherapy of Hepatocellular Carcinoma

Rex Cheung

Article Type: Short Communication | First Published: October 27, 2014

Hepatocellular carcinoma (HCC) is a primary liver cancer secondary to chronic liver conditions such as hepatitis Bvirus (HBV) and C virus (HCV) infections, obesity and alcoholism. HCC is the sixth most common solid tumor, and third most lethal cancer globally. Thre may be a gender diffrence in the development and outcome of chronic liver diseases. In U.S., the incidence of HBV infection has declined since the introduction of HBV vaccination in 1981. But approximately 350 million of global popula...

 Open Access DOI:10.23937/2378-3419/1/1/1006

Knowledge, Attitude and Screening Behaviour of Benue State University Male Students towards Prostate Cancer Awareness

Joyce M.Terwase, Chioma C. Asuzu and James A. Mtsor

Article Type: Research Article | First Published: October 18, 2014

The study investigated the influence of knowledge, attitude and screening behaviour of Benue State University Male Students towards prostate cancer awareness. Five research questions and research hypotheses guided the study. The study was a cross-sectional design utilizing a pretested 34-item Prostate Cancer Questionnaire (PCQ) (Cronbach’s alpha of 0.62) to collect information about knowledge, attitude and screening behaviour regarding prostate cancer among Benue State University Male students M...

 Open Access DOI:10.23937/2378-3419/1/1/1005

Squamous Cell Carcinoma and Squamous Differentiation Histologic Variant of Urothelialcarcinoma of Urinary Bladder: Oncological Outcome Following Definitive Surgical Treatment

Mohamed Wishahi, Hossam Elganzoury and Mohamed Badawy

Article Type: Research Article | First Published: September 29, 2014

Objectives: To investigate the impact of variant histologic patterns of urothelialcarcinoma of the bladder on oncological outcomes of patients treated with Radical Cystectomy (RC). Three histologic patterns were evaluated: Urothelial Carcinoma (UC), Squamous Cell Carcinoma (SCC), and urothelial carcinoma with Squamous Differentiation (SqD). Materials and methods: Retrospective archival study included 258 patients treated with RCfor muscle-invasive carcinoma. Data were reviewed in demographic a...

 Open Access DOI:10.23937/2378-3419/1/1/1003

Is Allogeneic Hematopoietic Cell Transplantation Still an Option for Chronic Lymphocytic Leukemia in the Era of BTK Inhibition?

Josh D. Simmons and Jeremy Pantin

Article Type: Editorial | First Published: September 08, 2014

Chronic lymphocytic leukemia (CLL) remains the most common adult leukemia in Western countries. Over the last several decades, there has been an evolution in therapeutic options from single-agent alkylating agents to purine analog-containing regimens, as well as chemo-immunotherapy combinations. Despite the high initial response rates reported with conventional chemo-immunotherapy, patients invariably relapse and may subsequently develop resistance to further conventional therapy.Unfortunately, ...

 Open Access DOI:10.23937/2378-3419/1/1/1002

Isnt it the Timing for Physics Guidelines on High Dose Rate (HDR) Brachytherapy for Localized Prostate Cancer?

Yongbok Kim

Article Type: Editorial | First Published: August 23, 2014

Prostate cancer has been known as the most frequently occurring (233,000 estimated new cases in 2014) and the secondly death-causing (29,480 estimated deaths in 2014) for men in the United States of America. Based on the extension of tumor, prostate cancer is staged in the Tumor-Node-Metastasis (TNM) scoring system. Depending upon clinical TNM staging, prostate-specific antigen (PSA) level (ng/mL) and pathologic biopsy denoted as Gleason sum score (GSS), localized prostate cancer patients are ca...

 Open Access DOI:10.23937/2378-3419/1/1/1001

International Journal of Cancer and Clinical Research- Commited to Ensure Quality Publication in Cancer Research

Sulma I. Mohammed

Article Type: Editorial | First Published: August 20, 2014

With great pleasure we welcome you to the inaugural issue of the International Journal of Cancer and Clinical Research. We envision this journal to provide a platform for all cancer researchers around the world to publish their high quality findings in cancer and clinical research as well as a venue to nurture researchers and young investigators in developing countries. The journal aims to accelerate the pace of research, discovery and innovation in clinical research around the globe....

Volume 1
Issue 1