Open Access DOI:10.23937/2378-3419/1410095
What the Oncologist Needs to Know about Axillary Web Syndrome
Ray C Mayo and Jessica Leung
Article Type: Case Report | First Published: June 30, 2018
A 60 yr female underwent bilateral skin sparing mastectomy with bilateral sentinel lymph node biopsies. Two months after her surgery, the patient began to notice increasing constant "pain and stiffness" in her shoulders bilaterally and difficulty "reaching overhead". Upon presentation to her health care team, she was noted to have impaired shoulder range of motion bilaterally related to bilateral thick axillary cords....
Open Access DOI:10.23937/2378-3419/1410094
Axillary Web Syndrome: What the Radiologist Needs to Know
Ray C Mayo
Article Type: Case Report | First Published: June 14, 2018
A 60 yr African American female was called back from her annual screening mammogram for an asymmetry in the upper outer quadrant of the left breast on the MLO view. Ultrasound revealed a 1.7 cm irregular hypoechoic mass with indistinct margins. Additionally multiple sub-centimeter non-contiguous hypoechoic satellite masses extended towards the nipple. One axillary node showed focal cortical thickening. Subsequent biopsy of the 1.7 cm mass and most anteriorly located satellite mass showed invasiv...
Open Access DOI:10.23937/2378-3419/1410093
Basosquamous Carcinoma: Report of Two Cases and Review of Literature
CH Saadani, H Baybay, H ElMahi, KH Elboukhari, S Gallouj, I SOUAF and FZ Mernissi
Article Type: Case Report | First Published: June 13, 2018
Basosquamous cell carcinoma (BSCC) or metatypical carcinoma is a poorly known cutaneous tumor that is considered as an aggressive type of basal cell carcinoma with an increased risk of recurrences and metastases. The most common onset is in the head and neck region....
Open Access DOI:10.23937/2378-3419/1410092
Quantification of Dosimetric Effects of Dental Metallic Implant on Volumetric-Modulated Arc Therapy Plans
Chun-I Lin, Yuanming Feng, Wenhuan Jiang and Zhibin Huang
Article Type: Original Research | First Published: May 30, 2018
CT images with the presence of metallic implants may cause severe metal artifacts with incorrect CT numbers, which lead to inaccurate dose calculation in RT planning. The goal of this study was to evaluate the dosimetric impact of metallic implants that correlates with the size of targets and metallic implants and the distance between the two on volumetric-modulated arc therapy (VMAT) plans for head and neck (H&N) cancer patients with dental implants....
Open Access DOI:10.23937/2378-3419/1410091
Which Has Better Dosimetry in Retroperitoneal Sarcoma: Rapid Arc or 3D Conformal Radiotherapy Techniques?
MW Hegazy, B Moftah and O Hassad
Article Type: Research Article | First Published: April 26, 2018
Our study was on 10 patients with RPS diagnosed and treated at king Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia, planned for pre or postoperative radiation therapy with prescribed dose of 45Gy in 25 fractions. In both techniques, we looked at planning target volume (PTV) coverage, dose homogeneity and organs at risk dose (stomach, bowel, liver, kidneys and spinal cord)....
Open Access DOI:10.23937/2378-3419/1410090
A Literature Review on Current Evidence of Immune Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer
Vineet Kwatra, Jose Roca, Sophie Merrick, Ruhe Chowdhury, Eleni Karapanagiotou and Rohit Lal
Article Type: Literature Review | First Published: April 18, 2018
Immune checkpoint inhibitors are changing the landscape in management of advanced non-small cell lung cancer. Programmed cell death protein-1 (PD-1) and cytotoxic T-lymphocytes antigen-4 (CTLA-4) are two important co-inhibitory receptors which can lead to suppression of T-cell function when bound to its ligands. Results from multiple large randomised phase 3 trials have shown a significant improvement in overall survival with durable response in selected group of patients following immune checkp...
