International Journal of

Cancer and Clinical ResearchISSN: 2378-3419

Archive

 Open Access DOI:10.23937/2378-3419/1410120

Performance of Three Prognostic Models in Critically Ill Patients with Cancer: A Prospective Study

Frank D Martos-Benitez, PhD, MD, Hilev Larrondo-Muguercia, MD, David Leon-Perez, MD, Juan C Rivero-Lopez, MD, Versis Orama-Requejo, MD and Jorge L Martinez-Alfonso, MD

Article Type: Original Article | First Published: July 17, 2019

Predicting mortality is one of the greatest challenges for critical care physicians. Severity scoring systems integrate clinical data to estimate the probability of death, which can be used to facilitate resource utilization or continuing quality improvement and to stratify patients for clinical research. Prospective validation in different populations of critically ill patients improves the applicability of the model to these settings. Furthermore, the performance of a prognostic score must be ...

 Open Access DOI:10.23937/2378-3419/1410119

Utility of Magnetic Resonance Imaging (Imaging) in Target Volume Definition for Radiosurgery of Acoustic Neuromas

Omer Sager, Ferrat Dincoglan, Selcuk Demiral, Hakan Gamsiz, Bora Uysal, Bahar Dirican and Murat Beyzadeoglu

Article Type: Original Article | First Published: June 20, 2019

Acoustic neuromas, also known as vestibular schwannomas are benign and slow-growing tumors arising from neural crest-derived Schwann cells. Treatment of acoustic neuromas targets to achieve local control while preserving hearing without comprimising cranial nerve functionality. In this context, radiosurgery in the form of Stereotactic Radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) offer viable therapeutic options for effective management. Multimodality imaging has gained utm...

 Open Access DOI:10.23937/2378-3419/1410118

Frailty as a Prognosis Factor in Cancer for the Elderly

Miguel Angel Acosta-Benito, Rosa Ana Garcia-Pliego, Jaime Barrio-Cortes and Veronica Rodriguez-FernAndez

Article Type: Research Article | First Published: June 20, 2019

Frailty is a geriatric syndrome related to adverse health outcomes in the elderly, due to a decrease systems' functional reserve. Cancer is a common pathology in the elderly, and we need tools for identifying the response to treatment and prognosis of elderly cancer patients. This short revision aims to assess the significance of the detection of frailty in the elderly patient with a tumor as a possible prognostic factor in terms of mortality, and the impact of the 2013 Frailty Consensus in the ...

 Open Access DOI:10.23937/2378-3419/1410117

Current Recommendations of Radioactive Seed ~ (125)I Implantation in Lung Brachytherapy: Moving Forward in Medical Care

Wang Yuchan, Yuan Gengbiao, Lee Changyi, Ran Lifeng and Yang Wei

Article Type: Review Article | First Published: June 20, 2019

Isotopes of radioactive iodine have a persistent lethal effect on the uncontrolled proliferation of tumor cells with a definite curative effect on tumors. It has been proved, up to 87.2% of 3-year's survival rate that could be achieved by radioactive seeds. Iodine-125 radioactive seeds have a long half life and low energy with excellent stable outcomes. Various effective isotopes with advanced techniques are used to place radioactive sources directly into a tumor, tumor bed in treating lung canc...

 Open Access DOI:10.23937/2378-3419/1410116

Breast Cancer Survivors: Is Routine 'Mammographic Only' follow up Imaging Enough or is it Time for Personalised follow up?

Gaurav Jyoti Bansal, Thomas Telford and Kevin Pinto

Article Type: Original Article | First Published: June 20, 2019

Breast cancer is the most common cancer in women, accounting for approximately 15% of all cancers. Over 85% of these people survive beyond 5 years after diagnosis, due to continual progressions in early detection and treatment quality. Despite advances in detection and treatment, 20-30% of patients develop local relapse or distant metastasis. Molecular subtyping of breast cancers based on receptor expression has been introduced in clinical practice and has developed into an important tool in pre...

 Open Access DOI:10.23937/2378-3419/1410115

Breast Fibromatosis: Case Report, Case Series, and Mini Review

Alicia Huff Vinyard, DO, Rachel Berger, MS-IV, TolgaOzmen, MD and Eli Avisar, MD

Article Type: Case Report | First Published: June 15, 2019

Fibromatosis of the breast is a rare, benign tumor, lacking metastatic potential, but can be aggressive and create issues with loco-regional control if not adequately treated. In the literature, fibromatosis of the breast is often discussed only in case reports and small case series. The consensus on treatment remains wide local excision, however, other therapies have been described. In discussion of an interesting case presentation of what we have defined as secondary breast fibromatosis, we re...

 Open Access DOI:10.23937/2378-3419/1410114

A Single Institution Study Experience of Secondary Breast Angiosarcoma after Breast Conserving Treatment: Multidisciplinary Management

Angela Strazzanti, MD, Claudio Trovato, MD, Santi Gangi, MD, Dario Marletta, MD, Roberto Milazzotto, MD and Corrado Spatola, MD

Article Type: Multidisciplinary | First Published: May 08, 2019

The aim of this study, focusing on a small number of cases, is to deal with the angiosarcoma of the breast, representing less than 1% of all soft tissue breast tumors, and finally share our experience. As a consequence of breast-conserving therapy (BCT) that is the standard treatment nowadays, a new type of angiosarcoma has been highlighted: Radiation-Induced Angiosarcoma (RIAS). Here is reported a retrospective analysis of RIAS patients' characteristic features, together with an account of the ...

Volume 6
Issue 3