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International Journal of

Cancer and Clinical ResearchISSN: 2378-3419

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 Open Access DOI:10.23937/2378-3419/1410132

A Novel Combined Methodology for Isolation and Detection of Circulating Tumor Cells based on Flow Cytometry and Cellular Filtration Technologies

Nikolaos G Grigoriadis, Konstantinos A Kyritsis, Melpomeni G Akrivou, Lefki-Pavlina N Giassafaki and Ioannis S Vizirianakis

Article Type: Original Article | First Published: February 08, 2020

Cancer cell presents a dynamic nature that evolves over time in its microenvironment through a complicating molecular and cellular interaction network. Despite the progress already achieved in the imaging technologies and the molecular tools used for tumor cell diagnosis and treatment approaches, metastasis still remains a major hindering factor that limits clinical outcomes. Circulating tumor cells (CTCs) present the potential in providing critical information to understand the metastasis proce...

 Open Access DOI:10.23937/2378-3419/1410131

Palmoplantar Erythrodysesthesia Associated with Capecitabine, Epidemiological Mapping and Risk Factors in Morocco

Tarik Hanafi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Brief Reports | First Published: January 27, 2020

A prospective cohort of a descriptive and analytical study, including sixty-one cases of Palmoplantar erythrodysesthesia in patients treated with capecitabine. The objective of this study is to determine an epidemiological mapping of Palmoplantar erythrodysesthesia in cancer patients on capecitabine treatment and to identify possible risk factors. The incidence of PPE was 64%. The median age of the patients who developed PPE was 54 years. 70% of the cohort was female, breast neoplasia represente...

 Open Access DOI:10.23937/2378-3419/1410130

Hyperpigmentation Associated with Anti-Tumor Chemotherapy: A Series of 54 Cases, Demo-Topographic Aspects and Interest of the Dermatological Intervention

Tarik Hanafi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Case Series | First Published: January 27, 2020

Three-year prospective study, from April 2016 to May 2019, including patients followed in oncology for malignant neoplasia, who developed hyperpigmentation following the start of antitumor chemotherapy for digestive, mammary and hematologic neoplasms, including the following molecules: 5 Fluorouracil, Tegafur, Cyclophosphamides, and Doxorubicin, in an isolated or combined mode. The study enrolled 54 patients, with an average age of 48 years and extremes ranging from 22 years to 67 years, with a ...

Volume 7
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