Pancreatic Autoantibodies in Sudanese Children with Newly Diagnosed Type 1 Diabetes Mellitus
Yahya Rabab Mahdi, Urwa Hashim and Abdullah MA
Article Type: Research Article | First Published: May 13, 2019
Immunepositive type one diabetes mellitus is the commonest cause of diabetes in children worldwide. Seronegative cases are said to be more common among black Africans. In a previous study in Sudan 46% of cases were found to have positive GAD antibodies. The aim of this study was to find out the prdevalence of pancreatic autoantibodies among multiethnic group of newly diagnosed Sudanese children by testing for multiple antibodies and to see how common are seronegative cases as reported in black A...
Prevalence of Proteinuria among Type 2 Diabetic Patients in Dhamar Governorate, Yemen
Abdulqawi Ali Al-Shammak, Abdullatif Daiffallah Ali and Hussein Al Jermozy
Article Type: Research Article | First Published: May 09, 2019
Diabetic nephropathy remains the most common cause of end-stage renal disease (ESRD) worldwide. Microalbuminuria is the first clinical sign of renal dysfunction in patients with diabetes mellitus. A urine total protein: creatinine ratio (TPCR) is a convenient and inexpensive measure of proteinuria and could be used to predict the presence of microalbuminuria in diabetic patients. The aim of this study was to assess the prevalence and associated risk factors of proteinuria among type-2 diabetic p...
Effects of Fractionated Neem Leaf Extract (IRC) on Blood Glucose Level in Alloxan Induced Diabetic Wistar Rats
Okpe Aaron C, Shu Elvis N, Nwadike kenneth I, Udeinya Iroka J, Nubila, Nkoyo I and Aniagor Ebele N
Article Type: Research Article | First Published: April 04, 2019
This study evaluated the hypoglycaemic effects of fractionated neem leaf extract (IRC) on alloxan induced diabetic wistar rats. IRC dissolved in phosphate buffered saline (PBS) PH 7.2 was administered as 50 mg/kg, 500 mg/kg, 1000 mg/kg, 2000 mg/kg single doses and 5 mg/kg, 50 mg/kg, 250 mg/kg and 500 mg/kg repeated doses in the diabetic rats while in the normoglycaemic rats 100 mg/kg and 250 mg/kg were used respectively. The positive control groups received single and repeated doses of glibencla...