Journal of

Dermatology Research and TherapyISSN: 2469-5750

Archive

 Open Access DOI:10.23937/2469-5750/1510017

Fluorescence in Situ Hybridization (FISH) Copy Number Abnormalities at 6p (RREB1), 6q (MYB), and 11q (CCND1) Reliably Distinguish Metastatic Versus Benign Melanocytic Lesions

Zaid Hindi, Michael Sidiropoulos, Ayman Al Habeeb, Danny Ghazarian, Niloufar Hosseini and Kenneth J. Craddock

Article Type: Original Research | First Published: February 29, 2016

Multicolour FISH was performed using a commercially available probeset (Abbott Laboratories, Abbott Park, IL), on formalin-fixed, paraffin-embedded tissue samples from 40 tumours: 20 benign melanocytic nevi, and 20 metastatic melanomas within lymph nodes, as determined by histologic assessment. Fluorescent signals for each probe were enumerated by 2 observers in 30 cells each per lesion....

 Open Access DOI:10.23937/2469-5750/1510016

Geometric Botulinum Toxin Injections: A Simplified Reproducible Approach for Symmetric Face Rejuvenation

Hussein Ghanem and Heba Darwish

Article Type: Review Article | First Published: February 29, 2016

Different approaches have been described for botulinum toxin (BTX-A) injections for face rejuvenation. Most techniques are based on the experience of the injecting physician and his/her learning curve. We describe a simplified approach to achieve accurate reproducible symmetric results with physicians of variable experience levels....

 Open Access DOI:10.23937/2469-5750/1510015

A Rare Case of Erosive Pustular Dermatosis Involving the Upper Limb

Paul Ting-Yuan Cheng, Lissa Elaine Judd and Agneta Carol Fullarton

Article Type: Review Article | First Published: February 29, 2016

Erosive pustular dermatosis (EPD) is a cutaneous inflammatory condition, characterized by chronically non-healing lesions with sterile pustules and hyperkeratotic crusted erosions. Although rare, severe cases have been referred by dermatologists to plastic surgeons for management. The aim of this paper was to describe the presentation and management of extensive EPD as well as a review of current literature on this rare condition....

 Open Access DOI:10.23937/2469-5750/1510014

Targeting Myostatin Signaling in Skin Healing

Christoph Wallner, Marcus Lehnhardt and Bjorn Behr

Article Type: Short Review | First Published: February 17, 2016

Myostatin is a protein well described for its role in decelerating muscle anabolism. Most studies targeting the Myostatin pathway were performed in muscle wasting diseases. Recent studies unveil a potential approach to interfere with the Myostatin pathway to facilitate wound healing. We therefore reviewed the present literature for aiming the Myostatin pathway as a potential treatment option in impaired skin healing. The inhibition of Myostatin may facilitate wound healing through different ways...

 Open Access DOI:10.23937/2469-5750/1510013

Knowledge and Behaviors toward the Sun and Skin Cancer: A Study of Hispanics in New York and Florida

Kate V. Viola, Kameron S. Rezzadeh, Daniel G. Federman, Christine J. Mathew, Shasa Hu, Andrea D. Maderal, Steven R. Cohen and Robert S. Kirsner

Article Type: Research Article | First Published: January 16, 2016

Over 3 million skin cancers are diagnosed in the United States each year. While the incidence of skin cancer is lower in patients of Hispanic descent, a recent report by the Center for Disease Control (CDC) found melanoma incidence rates to be significantly higher in Hispanic women under the age of 50 as compared to Hispanic men; Hispanics had the highest incidence of acral lentigenous melanoma among all races and ethnicities....

 Open Access DOI:10.23937/2469-5750/1510012

Rapid Improvement of Hidradenitis Suppurativa Following Sleeve Gastrectomy

Jong-Seob Park, Ji-Sun Hong and Sang-Moon Han

Article Type: Case Report | First Published: January 16, 2016

Severe obesity is commonly associated with dermatologic disorders such as intertrigo, psoriasis and hidradenitis suppurativa (HS). HS is a chronic inflammatory skin disease characterized by clusters of nodules, cysts, and abscesses that commonly affects hair bearing areas such as axilla, groin and perianal regions. Treatments of HS are complicated and vary depending on presentation and severity of the disease. We report here, the case of a 36-year-old female who showed rapid improvement of long-...

Volume 2
Issue 1