A New Way to Inhibit IL-17 in Psoriasis: Real-Life Use of Brodalumab Goes Beyond Clinical Trials Expectations
Mario Valenti, Paola Facheris, Giulia Pavia, Alessandra Narcisi, Riccardo Borroni and Antonio Costanzo
Article Type: CASE SERIES | First Published: December 30, 2019
Psoriasis is a common inflammatory skin disease that is estimated to affect about 2-4% of the population, with rates varying across ethnic groups and geographical regions. Biotechnological (more commonly called biologic drugs) drugs have shown great results in treating severe forms of psoriasis. Biologic agents that specifically block the IL-17 pathway have shown promising results with regard to efficacy and safety. Specific IL-17 inhibitors are represented by Secukinumab and Ixekizumab, fully h...
Psychosocial Impact of Rosacea on Women
Mohammed Al Abadie, Farlin Asharaff and Dina Al Abadie
Article Type: Research Article | First Published: September 09, 2019
Rosacea is found in approximately 10% of the general population and is known to mainly affect people from 30 to 60 years of age. It is more prevalent in female population as opposed to male population (with the exception of phymatous rosacea where majority of affected patients are adult male). A 2012 study consisting of 60,042 patients in the United Kingdom identified that 61.5% of patients with rosacea was female. Further studies suggest that rosacea has a greater impact on quality of life of f...
Hyperchromic and Erythematous Pityriasis: Case Report and Review of the Literature
Medina Andrade Luis Angel, MD, Laura Guadalupe Medina Andrade, MD, Lizbeth Elisa Oropeza Lopez, MD, Andrea Marianne Rodriguez Valencia, MD, Haizel Valencia Romero, MD, Angel Adrian Moreno Pina, MD, Araceli Esteban Chaparro, MD, and Alberto Robles Mendez Hernandez, MD
Article Type: Review Article | First Published: July 31, 2019
Pityriasis versicolor is a superficial fungal infection of the skin, characterized by pigmentary changes secondary to the colonization of the stratum corneum by a lipophilic dimorphic fungus known as Malassezia sp. Of this genus, 7 species known as the causative agent of pityriasis versicolor, the most frequently isolated species is M. Globosa. This skin disease occurs worldwide but predominates in the tropical, warm, and humid climate. Malassezia sp classified as dimorphic fungi since it behave...