Open Access DOI:10.23937/2469-5750/1510094
Treatment of Scar Contracture with Intralesional Jet-Assisted Injection of Hyaluronic acid
Daniel Cassuto and Yuri Vinshtok
Article Type: Case Series | First Published: December 30, 2020
Scar hypertrophy and keloid transformation very often present the cause of contracture. All current options for medical treatment of contracture have failed to give an immediate or near-time relief. In this case series we implemented a jet-injection method for intralesional delivery of hyaluronic acid and successfully achieved relief of surgical and burn scar contractures. The liquid jet permits an easy and tolerable penetration of hyaluronic acid into firm scar tissue. Biomolecular effect of HA...
Open Access DOI:10.23937/2469-5750/1510093
Therapy of Leprosy - Present Strategies and Recent Trends with Immunotherapy
Divya Chauhan, Raj Kamal and Aditya Saxena
Article Type: Review Article | First Published: December 04, 2020
Leprosy is a complex infectious diseases cause by Mycobacterium Leprae. As the nation is passing through the eradication phase of leprosy, reports are suggesting a change in epidemiology and symptomatology of the disease. Current therapeutic strategies like multidrug therapy (MDT) although effective in treating the majority of cases but not sufficient to eradicate still the new leprosy cases alone and with the complication of diseases like deformities, relapses, and recurrence of cases are occur...
Open Access DOI:10.23937/2469-5750/1510092
Skin Vesicles: Rare Presentation of Mycosis Fungoides
Dominique Fonseca Rodrigues Lacet, MD, Vinicius Cardoso Nóbrega, MD, Mariangela Esther Alencar Marques, MD, PhD, Silvio Alencar Marques, MD, PhD and Cristiano Claudino Oliveira, MD, PhD
Article Type: Case Report | First Published: November 30, 2020
Mycosis fungoides (MF) is the most common cutaneous lymphoma, accounting for about half of the cases (14), with many clinical and morphological variants (01). One of them is represented by the bullosa form (MFB), which is uncommon, with only 20 cases reported (05) in the literature. We present the case of a young patient whose diagnosis was made through skin biopsy associated with immunohistochemistry (IHC) and immunofluorescence (IF), aiming to discuss the pathophysiological possibilities for t...
Open Access DOI:10.23937/2469-5750/1510091
Diffuse Cutaneous Systemic Scleroderma with Secondary Infection: A Case Report
Anastasia Wibianto and Irene Dorthy Santoso
Article Type: Case Report | First Published: November 30, 2020
Scleroderma (systemic sclerosis or SSc) is a connective tissue disease of unknown cause, characterized by skin and visceral organs fibrosis and microvascular abnormalities. The prevalence of these patients is relatively low with 50- 300 cases per 1 million population and the incidence of 2.3- 22.8 cases per 1 million population per year. The risk for women is higher than men with a ratio of 3:1 and majority age 30-50 years. Diagnosis is based on clinical features and investigations. Management i...
Open Access DOI:10.23937/2469-5750/1510090
Epidemiological, Clinical and Therapeutic Profile of Genodermatoses in Mali
Karabinta Y, Gassama M, Diakité B, Guindo B, Keita A, Thiam H, Savané M, Sylla O, Dicko A, Kanouté A and Faye O
Article Type: Original Article | First Published: October 06, 2020
Long considered as orphan diseases because of their poorly estimated frequency. Genodermatoses are more and more encountered in the world. They have been reported in all ethnic groups, including African blacks. In Mali, ethnic diversity and the frequency of consanguineous marriage justify the interest of this study. To determine the prevalence of genodermatoses in Mali, to describe their clinical and therapeutic aspects. It was a descriptive cross-sectional study of all cases of genodermatoses d...
Open Access DOI:10.23937/2469-5750/1510089
Effect of Sublingual Isolated Transfer Factors in a Case of Therapy Resistant Periungual Warts
Marcella Nascimento e Silva, MSc, MD and Karla Gonçalves, Pharm.B
Article Type: Case Report | First Published: August 08, 2020
Periungual warts (PW), also known as verruca vulgaris, are caused by the human papilloma virus and appear as skin lesions located around the nailfold but can also affect the nail plate. Unfortunately, some of the therapies mentioned are destructive by nature and can also damage the nail matrix, hyponychium or underlying bone. Here we describe a patient resistant to a range of standard treatments. His clinical condition dramatically improved after use of isolated transfer factors (TF)....
Open Access DOI:10.23937/2469-5750/1510088
New Approachment of Creeping Eruption Management
Sukmawati Tansil Tan and Yohanes Firmansyah
Article Type: Case Report | First Published: July 23, 2020
Cutaneous larva migrans (CLM) is a zoonotic infestation caused by penetration and migration of filariform larvae into the epidermal layer of skin derived from dogs and cats, namely Ancylostoma braziliense and Ancylostoma caninum. Infective filariform larvae penetrate the surface of the skin, and migrate beneath the epidermis by leaving prominent linear or serpiginous lesions called 'creeping eruption'. One case was reported of CLM with the main complaint of being very itchy and serpiginosa lesio...
