International Journal of

Immunology and ImmunotherapyISSN: 2378-3672


 Open Access DOI:10.23937/2378-3672/1410026

Visions of the Hereafter: Releasing the Brakes of the Immune System by Checkpoint Inhibition Immunotherapy

Isabel C Hageman, Frans J van Overveld and Ger T Rijkers

Article Type: Review Article | First Published: July 24, 2017

Activation and control of the immune system is regulated by costimulatory molecules as well as by checkpoint inhibitors. Checkpoints are essential in maintaining self-tolerance and minimizing collateral damage by modulating the immune response....

Volume 4
Issue 1