Open Access DOI:10.23937/2378-3672/1410026
Visions of the Hereafter: Releasing the Brakes of the Immune System by Checkpoint Inhibition Immunotherapy
Isabel C Hageman, Frans J van Overveld and Ger T Rijkers
Article Type: Review Article | First Published: July 24, 2017
Activation and control of the immune system is regulated by costimulatory molecules as well as by checkpoint inhibitors. Checkpoints are essential in maintaining self-tolerance and minimizing collateral damage by modulating the immune response....
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