Vaccine production and immunization of the susceptible population against novel coronavirus (COVID-19) is the most important public health strategy in controlling and preventing the spread of disease. Considering the absence of a vaccine for COVID-19, physicians have to treat symptomatically using potential antiviral drugs (e.g. Tadalafil, Atorvastatin, Telmisartan, Ribavirin, Dipyridamole, Chloroquine phosphate and so forth). In such circumstances, the main question may arise on how we can chan...

Neutrophils are the most abundant leukocytes in humans and among the first cells to arrive on the site of inflammatory immune response. Due to their key role in inflammation, neutrophil functions such as locomotion, cytokine production, phagocytosis, respiratory burst and release of extracellular traps are extensively studied. In the presentstudy, we present a simplified neutrophil isolation protocol which has excellent reproducibility and low cost. Taken together, our findings point to the fact...

Asthma is one of the most common chronic diseases worldwide affecting approximately 300 million individuals. Asthma or anaphylaxis are allergic diseases essentially characterized by eosinophilia and mast cells release histamine which is responsible for the production of IgE. Nevertheless, neutrophils are highly implicated and it is demonstrated in about 50% of asthma cases. Consecutive to bronchial allergen challenge for example, there is an influx of neutrophils in proximal and distal airways. ...