International Journal of

Medical Nano ResearchISSN: 2378-3664


 Open Access DOI:10.23937/2378-3664/1410018

Protease Biosensors Based on Peptide-Nanocellulose Conjugates: From Molecular Design to Dressing Interface

J Vincent Edwards, Krystal R Fontenot, Nicolette T Prevost, David Haldane, Nicole Pircher, Falk Liebner, Alfred French and Brian D Condon

Article Type: Research Article | First Published: August 19, 2016

The development of point of care diagnostic protease sensors applied to wound healing has received increased interest in chronic wound treatment as an interface for chronic wound dressings. Biosensor technology and the use of nanomaterials have grown exponentially in recent years. A biosensor is fundamentally a biomolecule (functioning as a transducer) attached to a transducer surface, which is activated by a biochemical property that prompts a detection signal specific to a target biomarker. Fo...

 Open Access DOI:10.23937/2378-3664/1410017

Ovarian Cancer Treatment by Suicide Gene Therapy: Beauty of Nanotechnology in Medicine

Abhimanyu Thakur, Mahadi Hasan MA Shahed, Aishwarya Roy and Nabila Sayed

Article Type: Short Commentary | First Published: February 09, 2016

There has been a global interest worldwide in the recent trend of medical researches, which is basically a merge up between basic biology and engineering tools/technology. Imaging, microfluidics, nanofluidics, surface plasmon resonance (SPR) sensor systems, etc. are the widely used engineering tools in medical researches and has given effective clinical results. The most effective and widely used technology amongst these would be nanotechnology which employs methods like nano drug delivery, nano...

 Open Access DOI:10.23937/2378-3664/1410016

Studying Complex Interaction of B2H4 with HOR(R = H, CH3) and Nhn(CH3)3-N (N = 0-3) Molecules

Reza Tayebee and Abedien Zabardasti

Article Type: Research Article | First Published: February 02, 2016

Borane complexes are extensively studied and have even been the subject of Nobel Prize by Brown [1]. Many scientific data exist that have shown that boron is an essential microelement in animal cells. With the knowledge that borate linkages function in cell-to-cell adhesion, it has been hypothesised that boronates target structural glycoproteins located along the cytoskeletonplasma membrane-cell wall assembly....

 Open Access DOI:10.23937/2378-3664/1410015

Nanoparticles: From Diagnosis to Therapy

Derya Ilem-Ozdemir, Evren Gundogdu, Meliha Ekinci and Makbule Asikoglu

Article Type: Review Article | First Published: January 29, 2016

Cancer is a leading cause of death, the second most common cause, exceeded only by heart disease. Still, the current clinical imaging methods and treatments are in many situations unable to provide timely detection and curative therapy. The field of drug delivery stands to be significant advances in nanotechnology and benefits of novel nanotechnology in oncology already starts. New strategies are being designed to deliver chemotherapeutic drugs or imaging agents to the tumor at higher concentrat...

 Open Access DOI:10.23937/2378-3664/1410014

Estimating Binding Capability of Radiopharmaceuticals by Cell Culture Studies

Derya Ilem-Ozdemir, Meliha Ekinci, Evren Gundogdu and Makbule Asikoglu

Article Type: Review Article | First Published: January 02, 2016

Radiopharmaceuticals have applications in biologic research, drug discovery, diagnosis of human disease and molecular therapeutics for a wide variety of medical conditions. With the increasingly central role of radiotracers for non-invasive imaging of animal models and human research, small animal imaging centers are likely to have a growing interest in development of radiopharmaceutical science. Although animal experiments are giving the most valuable information about the drug behavior in the ...

 Open Access DOI:10.23937/2378-3664/1410013

Modification of the Uranyl Acetate Replacement Staining Protocol for Transmission Electron Microscopy

Santhana Raj L, Paramsavaran S, Koay BT, Izan Shahrina A and Siti Aminah N

Article Type: Review Article | First Published: January 02, 2016

A uranyl acetate replacement staining protocol has eliminated the need for highly toxic uranyl acetate in the electron microscopy laboratory. However, the method is results in undesirable charging effects when viewed under the transmission electron microscope and can be further improved. A modification of the uranyl acetate replacement staining protocol that simplifies the process is described. The modified method takes less time, and produces better contrast and less charging effects compared t...

Volume 3
Issue 1