International Journal of

Neurology and NeurotherapyISSN: 2378-3001


 Open Access DOI:10.23937/2378-3001/1410074

The Main Neurological Dysfunctions in Hyperargininemia-Literature Review

Andre Eduardo Almeida Franzoi, Marcelo Manukian Patti, Debora Delwing Dal Magro and Daniela Delwing de Lima

Article Type: Original Article | First Published: June 25, 2018

Arginine is an essential amino acid. This compound plays an important role in various body functions including cell division, wound healing, removal of ammonia, immune function, and release of hormones. The arginase 1 is a hepatic enzyme that is the faulty component in urea cycle. The urea cycle is represented in Figure 1 with focusing on arginine. When in normal function, the enzyme catalyzes the reaction of conversion of the arginine in ornithine and urea. However, in hyperargininemia, this en...

 Open Access DOI:10.23937/2378-3001/1410073

Rotigotine in Parkinson's Disease Patients: What is the Efficient and Tolerable Dose According with the Real Clinical Practice? An Open, Non-Controlled Multicenter Spanish-Study

Salazar G, Fragoso M and Codas J

Article Type: Original Article | First Published: April 26, 2018

Rotigotine is dopaminergic agonist (DA) with a high affinity for D3-dopaminergic receptors delivered through trans-dermal patch which has shown efficacy and tolerance in Parkinson's disease patients (PD) according with some articles published in the past. Whereas, most of the studies published on Rotigotine have shown efficacy to ameliorate the cardinal symptoms of PD at daily dose of 8 Mgs....

 Open Access DOI:10.23937/2378-3001/1410072

Evaluation of Retinal Nerve Fiber Layer and Optic Nerve Function in Patients with Obstructive Sleep Apnea Syndrome

Mualla Hamurcu, Selma Fırat, Suleyman Boynuegri, Ufuk Hamurcu, Murat Sinan SarCcaoglu, Selcan Ekicier Acar, B Seyma Durmus and Bulent CiftCi

Article Type: Research Article | First Published: April 25, 2018

Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder, with an estimated prevalence of 2% for women and 4% for men in the middle-aged population. It is characterized by the repetitive complete or partial collapse of the upper airway during sleep which causes the cessation (obstructive apnea) or significant reduction (obstructive hypopnea) of airflow. These respiratory events result in intermittent hypoxemia and hypercapnia, cortical arousals, and surges of sympathetic...

 Open Access DOI:10.23937/2378-3001/1410071

Susac Syndrome Successfully Treated with Mycophenolate Mofetile

Rocio Lopez Ruiz, Sara Eichau, Elena Calzado Rivas, Guillermo Navarro Mascarell, Juan Luis Ruiz-Pena and Guillermo Izquierdo

Article Type: Case Report | First Published: March 22, 2018

Susac Syndrome is an infrequent condition that is often misdiagnosed as Multiple Sclerosis. This syndrome is characterized by the clinical trial of encephalopathy, retinopathy with branch retinal artery occlusions and hearing loss....

Volume 5
Issue 1