Open Access DOI:10.23937/2378-3001/1410100
COVID-19 and Nervous System: Under Estimated Clinical and Prognostic Aspects
Alyne Barreto Mesquita de Goés, Bruno Barreira Cardoso, Francisco de Assis Fernandes Tavares, Rebecca Renata Lapenda do Monte, Renata Carneiro Melo, Irami Araújo- Neto, Renato Serquiz Elias Pinheiro, Amália Cinthia Meneses Rêgo and Irami Araújo- Filho
Article Type: Review Article | First Published: June 24, 2020
The coronavirus pandemic transformed the world abruptly due to the speed of transmission and high morbidity and mortality. Many deaths have been quantified, and the scientific community intensifies the search for molecular targets, protein sequences and polymorphismson SARS-CoV-2, to improve the clinical evolution and survival of patients. Initially, COVID-19 was described with respiratory changes, flu, and fever. With the spread of the disease, clinical manifestations were observed in other org...
Open Access DOI:10.23937/2378-3001/1410099
Intracranial Hemorrhage Associated with Sildenafil Use: A Very Rare Complication
GUNTEL Murat, CAN Hakan, GOK Fatma, TANGULEC Goncagul, BALIKEL Unal and USTA Busra Nur
Article Type: Case Report | First Published: April 29, 2020
Intracerebral hemorrhage (ICH) (International Classification of Diseases, 9th Revision) is a neurological deficit documented by brain CT or MRI showing the presence of an intracranial bleed in the parenchyma of the brain. ICH is a serious cerebrovascular condition associated with high mortality and morbidity in adults It can be classified as primary and secondary according to etiology. Primary intracranial hemorrhage often develops due to hypertension or amyloid angiopathy. Secondary intracrania...
Open Access DOI:10.23937/2378-3001/1410098
Blood Blister-Like Aneurysm of the Intracranial Internal Carotid Artery Associated With Extracranial Dissection of the Artery
Riccardo Russo, Fabrizio Venturi, Mauro Bergui and Gianni Boris Bradac
Article Type: Case Report | First Published: April 23, 2020
Blood blister-like aneurysms (BBAs) have been described as small aneurysmal bulges, more frequently arising from non-branching sites on the supra-clinoid internal carotid artery (ICA). Their etiology is still controversial. In our case the association of the BBA, presenting with a severe subarachnoid bleeding, and extracranial ipsilateral ICA dissection in a patient with fibromuscular dysplasia, could suggest that both lesions were due to the same pathologic process. The aneurysm was treated in ...
Open Access DOI:10.23937/2378-3001/1410096
Complications as Poor Prognostic Factors in Patients with Hemorrhagic Stroke: A Hospital-Based Stroke Registry
Rizaldy Taslim Pinzon and Vincent Ongko Wijaya
Article Type: Research Article | First Published: February 05, 2020
Stroke is one of the most important causes of global morbidity and mortality. In 2013, stroke was ranked second as the most common cause of death, responsible for 6.5 million deaths globally and the third most common cause of disability in the world. According to the latest world health organization (WHO) data published in 2017, stroke was the leading cause of death in Indonesia reached 332,663 or 19.79% of total deaths of the country. Stroke patients commonly experience medical complications su...
Open Access DOI:10.23937/2378-3001/1410095
Towards a Biological Definition of Alzheimer Disease
Kurt A Jellinger, MD
Article Type: Commentary | First Published: January 08, 2020
Alzheimer disease (AD), the most common form of dementia, is a heterogenous syndrome with various pathobiologically defined subtypes. The clinical diagnosis of probable AD is enabled by the recent ATN biomarker system, but the definite diagnosis is only possible at post-mortem according to the updated NIA-AA criteria. The recent developments in the clinical and neuropathological diagnosis of AD including its specific subtypes improving the evaluation of AD and its impact on public health are bri...
Open Access DOI:10.23937/2378-3001/1410094
Polymyositis in Adamantiades-Behcet's Disease
Carlos Arteaga Rodriguez, MD, MSc, Otto J Hernandez Fustes, MD, MSc, Renato Puppi Munhoz, MD, PhD and Olga Judith Hernandez Fustes, MD, MSc
Article Type: Case Report | First Published: January 04, 2020
Although Adamantiades-Behçet’s disease (ABD) has a worldwide distribution, it is considered rare in the Americas, with a prevalence of 0.12-0.33:100.000 in the United States. The characteristic triad of recurrent oral aphthous lesions, genital ulcers and iridociclitis occurring more often in young adults during their third or fourth decade of life was initially described by Hippocrates but gained it's classic eponym to acknowledge the Greek ophthalmologist from Asia Minor (nowadays part of A...
