Review Timeline | CrossMark Policy | ClinMed Features
logo
International Journal of

Pathology and Clinical ResearchISSN: 2469-5807

Archive

 Open Access DOI:10.23937/2469-5807/1510159

Adenoid Cystic Carcinoma of Thyroid - Unusual Primary Site and Diagnostic Considerations in Cytology

Vijayalakshmi Gudivada, MD, DipFRCpath, Parepalli Divya, MD, Pampa ch Toi, MD and Sreekanth Gaddam, MBBS, MSc

Article Type: Case Report | First Published: 2024/11/08

Adenoid cystic carcinoma (ACC) is a rare head and neck tumor, typically arising from both major and minor salivary glands and sweat gland epithelium. This case report presents a 38-year-old female with primary thyroid ACC, an exceedingly rare entity with only a very few cases reported in the literature. The patient presented with a solitary thyroid nodule, Fine needle aspiration cytology revealed basaloid cells in three-dimensional clusters with many luminal hyaline globules, consistent with ACC...

 Open Access DOI:10.23937/2469-5807/1510158

Targeted Metabolomic Profiling of High-Grade Gleason Score Distinguished from Low-Grade Gleason Score with Prostate Cancer in Blood Plasma using NMR Spectroscopy

Pradeep Kumar, Virendra Kumar, Rajeev Kumar, Sanjay Sharma, Sanjay Thulkar and M A Khan

Article Type: Research Article | First Published: 2024/11/07

Separating low-grade from high-grade Gleason score (GS) prostate cancer (PCa) is an important clinical challenge for identifying patients eligible for active surveillance, thereby reducing the risk of overtreatment. PCa is one of the most prevalent cancers among men, characterized by varying degrees of aggressiveness. Despite recent progress in precisely determining some of the molecular mechanisms that contribute to cancer progression, more targeted and focused predictive techniques are still n...

 Open Access DOI:10.23937/2469-5807/1510157

Metastatic Lobular Carcinoma Involving the Vulva as Initial Presentation of Disease in a Patient with Dense Breast Tissue

Shandice Waugh, Michael Deavers and Lavinia P. Middleton

Article Type: Case Report | First Published: 2024/11/03

We present the case of a 72-year-old woman with dense breast tissue and no initial mammographic signs of malignancy, who presented with a vulvar mass that was discovered to be metastatic lobular carcinoma from the breast. This is the first example documented in the English literature of metastatic lobular carcinoma involving the vulva as the initial presentation of disease. This case report highlights the pathologic features of this uncommon entity and its diagnostic challenges....

 Open Access DOI:10.23937/2469-5807/1510156

Prevalence of Pancreatic Intraepithelial Neoplasia among Resectable Pancreatic Specimens in a Private Tertiary Care Setting in Taiwan

Marissa Krizelda D Santos, MD, Ren Chin Wu, MD, Shih Chiang Huang, MD, Kwai Fong Ng, MD and Tse Ching Chen, MD

Article Type: Research Article | First Published: 2024/08/31

Pancreatic adenocarcinoma remains as the seventh most common cause of mortality in Taiwan (5-year survival rate of 5.2%). Pancreatic intraepithelial neoplasia is an established precursor of pancreatic adenocarcinoma. This study aims to investigate the prevalence, age distribution and variables associated with the presence of pancreatic intraepithelial neoplasia....

 Open Access DOI:10.23937/2469-5807/1510155

Histopathological Findings of Colonoscopic Biopsies from Sudanese Patients

Saeed Bashir Saeed Mohamed, Sahar Abdallah Mohamed Eltayeb, Sahar Hassan Mohamed Osman, Fatima Elbadri Mohammad Nour, Hafsa Adel Hassan Bashier, Namarig Elamin Babiker Mohamed Ahmed, Samah Batran, Aisha Adam Mohmmed, Fathelrahman AE Saaid, Ahmed Amin Mohammed and Hussain Gadelkarim Ahmed

Article Type: Research Article | First Published: 2024/08/02

Colorectal cancer (CRC) is the third most common malignancy and the second major cause of cancer deaths worldwide. The main aim of this study was to assess the histopathological findings of colonoscopic samples collected from Sudanese patients....

 Open Access DOI:10.23937/2469-5807/1510154

The Role of Cell Cycle Division 6 (CDC6) in Cancer: Breast Cancer as a Prototype

Yousif A Kariri

Article Type: Review Article | First Published: 2024/07/08

An increase in cancer-cell division (proliferation) is a distinctive feature of cancer and is acknowledge as a key cell-division checkpoint alteration in cancer cells. Breast cancer is well-known as a heterogeneous disease with variant molecular subtypes, responses to therapy and morphological characteristics, breast malignant cells are identified to deactivate cell-cycle checkpoints to support survival and proliferation. Cell-cycle division 6 (CDC6) plays an important role as a cell-cycle check...

Volume 10
Issue 2