Intravenous Immunoglobulin Therapy for Maintenance Therapy of Interstitial Lung Disease Due to Antisynthetase Syndrome
Angad Deengar, MD and Rahul Mutneja, MD
Article Type: Case Report | First Published: November 03, 2022
Antisynthetase syndrome (AS) is a rare autoimmune condition characterized by fever, Raynaud’s phenomenon, hyperkeratosis, inflammatory polyarthritis, and interstitial lung disease (ILD). The development of ILD in patients with antisynthetase syndrome (AS-ILD) portends a poor prognosis to an already rare and difficult to diagnose autoimmune disorder. We present the case of a 67-year-old Caucasian male who initially presented for evaluation of an abnormal chest radiograph, taken a few weeks afte...
Investigation of Sirtuins-1 and Matrix Metalloproteinase-9 Levels in the Bronchiectasis Patients
Deniz Kuruçay, Mustafa Doğan Bedir, Zehra Seyfikli and Dilara Ülger Özbek
Article Type: Research Article | First Published: October 23, 2022
Bronchiectasis refers to abnormal, usually permanent, dilatation of the bronchi and it is a clinical syndrome that usually presents with cough, sputum production, and recurrent chest infections with symptoms such as malaise, chest discomfort, hemoptysis (cough of blood), and weight loss. The aim of this study was to determine sirtuin-1 (SIRT-1) and matrix metalloproteinase-9 (MMP-9) levels in the serum of patients with bronchiectasis and to reveal whether there was a possible relationship betwee...