International Journal of

Stem Cell Research & TherapyISSN: 2469-570X


 Open Access DOI:10.23937/2469-570X/1410047

Human Umbilical Cord Blood Stem Cells and Chitosan Hydrogels Produce Similar Beneficial Effects in Acute Myocardial Infarctions and Ischemic Cardiomyopathies

Robert J Henning, Abraham Khan, David Whitaker and Narendra Sastry

Article Type: Original Research | First Published: June 26, 2017

We utilized two separate techniques, human Umbilical Cord Blood Stem Cells (hUCBC) and chitosan hydrogels, to limit acute myocardial infarction size and LV remodeling. Human Umbilical Cord Blood Mononuclear Cells (hUCBC), contain hematopoietic and mesenchymal stem cells. Chitosan is a polysaccharide....

 Open Access DOI:10.23937/2469-570X/1410046

Effects of Overexpression of C-Myc and Bcl-2 on Viability, Apoptosis and Differentiation of Dental Pulp Stem Cells

Waruna Lakmal Dissanayaka, Xiaofei Zhu and Chengfei Zhang

Article Type: Original Research | First Published: May 29, 2017

The development of cell lines with high cell density, controlled proliferation, apoptosisresistance, and easy adaptation into cultures of serum free media is essential for the success of tissue engineering strategies....

 Open Access DOI:10.23937/2469-570X/1410045

Secretome of Mesenchymal Stem Cells Grown in Hypoxia Accelerates Wound Healing and Vessel Formation In Vitro

Sushma Bartaula-Brevik, Anne Isine Bolstad, Kamal Mustafa and Torbjorn O Pedersen

Article Type: Original Article | First Published: February 20, 2017

Hypoxia is one of the factors that trigger the release of inflammatory and vasculogenic cytokines during tissue regeneration. Mesenchymal stem cells (MSC) with and without endothelial cells (EC) were cultured in vitro in normoxic and hypoxic environments. The mRNA expression of inflammatory and vasculogenic cytokines were evaluated at 1, 12, 24 and 48 hours. After 48 hours of incubation in normoxic and hypoxic conditions, supernatants termed as conditioned medium (CM) from each group were collec...

Volume 4
Issue 1