Open Access DOI:10.23937/2643-461X/1710063
COVID-19 Vaccine Acceptance and Hesitancy: A Continental Review
Olabode Ebenezer Omotoso, Tolulope Oladimeji, John Oluwafemi Teibo and Ayomide Oluwadarasimi Adebesin
Article Type: Review Article | First Published: June 09, 2022
There are various contributory factors that decide acceptance or ensure hesitancy among the populace which includes: Age, education, gender, residence, household income, marital status, religion, information source, access to vaccine and vaccine equity, etc. Major concerns, barriers, and motivators about vaccination were highlighted....
Open Access DOI:10.23937/2643-461X/1710064
Clinical Profile of the Diagnosis and Treatment of Human Brucellosis in Ghindae Zonal Referral Hospital, Northern Red Sea Region, Eritrea
Esayas T Mehari, MD, Dawit Kidane, Abraham Dawit Jeff, Feven T Mehari, Michael Ghebrezghabiher and Fitsum Kibreab
Article Type: Original article | First Published: June 13, 2022
The study aims to uncover the burden of brucellosis in Ghindae Zonal Referral Hospital, the therapeutic approach used at the hospital, and the outcome of treatment....
Open Access DOI:10.23937/2643-461X/1710060
Impact of a Group-Based Video and Interactive Group Session Addressing Diarrheal Disease, Helminthic and Schistosomiasis Infections, Hypertension and Diabetes on Short and Long- Term Improvement in Knowledge and Healthy Behaviors in Seroconcordant HIV-Negative Zambian Couples
Sharkey, MPH, DrPH (cand), R Parker, MSPH, KM Wall, PhD, K Malama, PhD, W Kilembe, MD, MSc, M Inambao, MD, MPH, A Tichacek, MPH, C Kwok, MPH, N Ahmed, MPH, DrPH, R Burke, MPH, RW Peeling, PhD and S Allen, MD, MPH
Article Type: Original Article | First Published: April 27, 2022
Non-communicable and neglected tropical diseases (NCD and NTD) contribute to high morbidity and mortality in Zambia. While the public health importance of NTD has long been recognized, prevalence of disease remains high. NCD are emerging as causes of morbidity and mortality. Knowledge of risk factors, diagnosis, management, and prevention of NCDs and NTDs in the general population is poor and as a result, low-cost commodities are insufficiently used. Urban couples recruited in five government he...
Open Access DOI:10.23937/2643-461X/1710061
Isothermal Amplification-Based Detection Platforms for Pathogenic Leptospira Species in Flood and Environmental Waters
Rubigilda Paraguison-Alili, Renmar M Dela Cruz, Analiza M Balaga and Winston A Palasi
Article Type: Original Article | First Published: April 27, 2022
Detecting the occurrence of pathogenic Leptospira spp. is vital for public health implications and epidemiological studies. Different isothermal-based techniques ascribed to loop-mediated isothermal amplification (LAMP) to detect Leptospira spp. in black rats and spiked environmental waters were evaluated. In this study, modified platforms were designed to detect the lipL32 gene encoding the major outer membrane lipoprotein of Leptospira spp. Standard and direct dry isothermal technique platform...
Open Access DOI:10.23937/2643-461X/1710059
Performance of GeneXpert in the Diagnosis of Tuberculosis in a Decentralized Area: Example of Hopital De La Paix, in Ziguinchor, Southern Senegal from 2016 to 2018
Kalilou Diallo, Ansoumana Diatta, Bruce Shinga Wembulua, Awa Camara, Habibou Sarr, Mame Ngone Coly, Alassane Diatta and Noel Magloire Manga
Article Type: Research Article | First Published: March 17, 2022
The Xpert MTB/RIF test is one of the innovative responses to the challenges of early diagnosis of tuberculosis and rifampicin resistance. Three years after the arrival of GeneXpert at La Paix hospital, we carried out this study in order to assess its contribution to the diagnostic process. This cross-sectional, descriptive and analytical study focused on suspected tuberculosis patients whose pathological products were analyzed at the unit of microbiology of La Paix hospital of Ziguinchor, Senega...
Open Access DOI:10.23937/2643-461X/1710058
Antimicrobial Resistance Patterns of Pseudomonas aeruginosa in a Vietnamese Tertiary Care Hospital
Thi Ha Vo, PhD, Pharm, Quang Hien Bui, BSc, Pharm, Hoang Hai Nguyen, PhD, MD and Hong Tham Pham, BSc, Pharm
Article Type: Original Article | First Published: March 17, 2022
Vietnam is one of the countries at high alert of antibiotic resistance. This study aimed to evaluate the antimicrobial susceptibility of P. aeruginosa isolates collected from a Vietnamese hospital in 2019. A retrospective review was conducted of all reports of P. aeruginosa isolates from the records of the laboratory of Nhan Dan Gia Dinh Hospital between January 01 2019 to December 31 2019. Of 224 samples, the most common infection from which P. aeruginosa was isolated was pneumonia in hospitali...
Open Access DOI:10.23937/2643-461X/1710057
Understanding the Systemic Effects of COVID-19: Possible Clues to Potential Therapeutic Approaches
Oritoke M Aluko, Saheed A Lawal, Celestine S Reuben, Sikirullai O Jeje and Omamuyovwi M Ijomone
Article Type: Review Article | First Published: February 18, 2022
The novel coronavirus disease (COVID-19) is an infectious disease caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is an acute respiratory disease that causes life-threatening symptoms. This virus directly or indirectly affects the various systems of the body. In the respiratory system, it causes pulmonary edema, impaired oxygen diffusing capacity, difficulty in breathing, etc. In the nervous system, it causes encephalitis, thrombo-embolitic stroke, Guillan-Barr...
Open Access DOI:10.23937/2643-461X/1710056
Analysis of IgG Responses to P. falciparum Antigens MSP1, MSP4-20 and MSP4-40 during Severe Malaria in Dakar, Senegal
Bruce Shinga Wembulua, Kalilou Diallo, Folly Mawulolo Gaba, Babacar Mbengue and Louise Fortes
Article Type: Original Article | First Published: February 07, 2022
Antibodies to merozoite surface antigens (MSPs), the primary targets of malaria vaccine research, are associated with low malaria morbidity. However, few studies have looked at the implications of their variations on the evolution of clinical-biological forms of severe malaria. This cross-sectional, prospective, and analytical study evaluates by ELISA the IgG responses directed against the antigens MSP1, MSP4-20 and MSP4-40 of P. falciparum during severe malaria in patients hospitalized in the i...
