Journal of

Toxicology and Risk AssessmentISSN: 2572-4061


 Open Access DOI:10.23937/2572-4061.1510035

A Comprehensive Assessment of Hepatotoxicity Induced by Engineered Nanoparticles- A Review

S V S Rana

Article Type: Review Article | First Published: October 17, 2020

Liver is the major detoxifying centre of the body. It removes xenobiotics and their metabolites through metabolism or biliary excretion. Hepatocytes constitute 80% of total liver mass and play a major role in storage, synthesis, metabolism and redistribution of essential molecules. Liver has been known to accumulate > 90% of nanomatrerials translocated from other organs. Bioconcentration of nanoparticles may lead to impairment of structure and function of hepatic cells. Therefore, it is critical...

 Open Access DOI:10.23937/2572-4061.1510034

Psychological Impact of Medical Professionals Handling COVID-19 Patients in Hospitals

Anirban Biswas, Saroni Biswas and Arijit Bhowmik

Article Type: Research Article | First Published: August 22, 2020

COVID-19 pandemic became a death troll and cause of unbearable psychological pressure for all and the pandemic situation has been considered as a national disaster in India. Present study identified the mental health status of the medical professionals in different hospitals handling COVID-19 patients. We collected psychological data of medical professional using online questionnaire and identified their psychological status following three tools namely, Generalized Anxiety Disorder (GAD), Depre...

 Open Access DOI:10.23937/2572-4061.1510033

Quantification and Risk Assessment of Heavy Metals in Groundwater and Soil of Residential Areas around Awotan Landfill, Ibadan, Southwest-Nigeria

Olagunju TE, Olagunju AO, Akawu IH and Ugokwe CU

Article Type: Original Article | First Published: July 29, 2020

Non-sanitary landfill poses enormous threats to lives. In this study, heavy metals in groundwater and soil of residential areas around Awotan landfill, Ibadan, Southwest-Nigeria were quantified and associated environmental and health risks were assessed within 1-150 m and 151-300 m radii. A total of 20 samples of groundwater and soil each were analysed for Pb, Cd, Cr, Ni, Cu, Fe and Zn using Atomic Absorption Spectrometry (AAS). Pb was above the WHO permissible limit in groundwater while Cd was ...

 Open Access DOI:10.23937/2572-4061.1510032

Reference Dose and Reference Concentration Rounding in IRIS: Risk Assessment Ramifications

Lawrence V Tannenbaum

Article Type: Original Article | First Published: April 10, 2020

Commonly, reference doses and reference concentrations, toxicity factors supporting non-cancer assessments for the chemical exposures of humans, are rounded values. While the U.S. EPA's Integrated Risk Information System rather evidently employs this rounding practice so as to arrive at toxicity values that are uniform and simple in appearance, the particulars of the rounding approach are only loosely discussed. The analysis provided here found that reference dose and reference concentration rou...

 Open Access DOI:10.23937/2572-4061.1510031

Epidemiology and Diffusion of Some Relevant Virus: Latitude, Air Pollutants and Humidity Role, Hypothesis of Work: Covid-19 Effect on the Air Pollution in Some World Region: What Implications?

Luisetto M, Ahmed Yesvi Rafa, Khaled Edbey, Ghulam Rasool Mashori, Farhan Ahmad and Oleg Yurevich Latyshev

Article Type: Research Article | First Published: April 09, 2020

Related some recent example of human virus diffusion and epidemiology is interesting to observe some facts related latitude, climate, air pollutants and other. In this work only few images are used to submit and hypothesis of work to better understand some process. Is interesting to observe that WUHAN is a region characterized by a specific air pollutants status and near two big river in a determinate latitude. Obviously, the human transmission and the relationship with animal transmission can n...

Volume 6
Issue 1