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International Journal of

Virology and AIDSISSN: 2469-567X

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 Open Access DOI:10.23937/2469-567X/1510046

Understanding the Facts and Minding the Gap of (HIV-1/HIV-2) Primate Research and Infectious Disease Laboratories in Africa

Chika Ejikeugwu, Peter Eze, Ifeanyichukwu Iroha, Charles Esimone, Michael Adikwu and Hirofumi AKARI

Article Type: Review Article | First Published: December 31, 2018

With over 2 million annual new infections of human immunodeficiency virus (HIV)-1, and more than 30 million HIV-1 infected people around the globe, the HIV-1 pandemic has continued to remain a front burner in the medical research community and an important public health debate. Till date, there is still no cure or vaccine for HIV-1 infection. Though current antiretroviral therapy (ART) is potent enough to reduce viral load of the infection to below detectable limits (< 50 copies/ml), antiretrovi...

 Open Access DOI:10.23937/2469-567X/1510045

Time to Major Adverse Reactions of Anti-Retroviral Drugs and its Predictors among Cohort of Patients Receiving Antiretroviral Therapy in Hosanna Hospital, Hosanna, Ethiopia: Retrospective Cohort Study

Likawunt Samuel Asfaw and Fikre Enquselassie

Article Type: Original Research | First Published: December 08, 2018

Antiretroviral therapy (ART) suppresses viral reproduction and stop progression of the disease process. Antiretroviral drug adverse reactions negatively influence antiretroviral treatment outcome. Incidence, type and time antiretroviral drug adverse reactions occur is not well documented. The purpose of this study was to investigate time to major antiretroviral drugs adverse reactions and its predictors among patients receiving ART in Hosanna, Ethiopia....

 Open Access DOI:10.23937/2469-567X/1510044

Infectious Characteristics of Ebola Virus

Manu Mitra

Article Type: Letter to Editor | First Published: November 07, 2018

One of the main feature of Ebola virus is that Ribonucleic acid (RNA) plays more significant part instead Deoxyribonucleic acid (DNA) similarly as its hereditary material. When RNA is mirrored, many more mistakes are made than when DNA is mimicked. This activates viruses like the Ebola viruses a predominantly high mutation rate when distinguished to DNA based viruses like smallpox or chickenpox. In the study of Ebola outbreak, experts found that the virus evolves much faster than it used to be i...

 Open Access DOI:10.23937/2469-567X/1510043

90-90-90, Epidemic Control and Ending AIDS: Global Situation and Recommendations

Reuben Granich, Somya Gupta and Brian Williams

Article Type: Review Article | First Published: September 17, 2018

Although human immunodeficiency virus (HIV) first came to our attention thirty-seven years ago, the acquired immunodeficiency syndrome (AIDS) which it causes is, without treatment, 100% fatal with devastating consequences for millions of people...

 Open Access DOI:10.23937/2469-567X/1510042

Microhomology of Viral/Host DNAs and Macrostructure of Herpesviral Genome

Felix Filatov and Alexandr Shargunov

Article Type: Research Article | First Published: September 01, 2018

In 2015, we described short continuous fragments of human herpesvirus DNA, identical to the cellular ones, which we called microhomology (hits) because of their small size (≥ 20 nt). We noticed that generally the increase in the density (D) of these hits in human herpesviruses is inversely proportional to a decrease in the pathogenicity of these viruses. In this small work, we are considering the question of the existence of more objective features of HHV DNA (which can accompany the dynamics ...

 Open Access DOI:10.23937/2469-567X/1510041

Modeling the HIV Epidemic: Why the 95-95-95 Target and ART Effectiveness Parameters Matter

Reuben Granich, Somya Gupta, Matt Wollmers, Mike Ruffner and Brian Williams

Article Type: Review Article | First Published: August 20, 2018

HIV remains a major global public health threat with one million HIV-related deaths, two million new infections and over 1 million HIV-associated TB cases each year. However, population-based studies suggest marked declines in incidence, prevalence and deaths in the countries in East and Southern Africa that have expanded antiretroviral treatment (ART) at the fastest rate in the world....

 Open Access DOI:10.23937/2469-567X/1510040

Viral Infections after Kidney Transplantation: An Updated Review

Ethem Unal and Ahmet Topcu

Article Type: Review Article | First Published: July 01, 2018

Infections are the major cause of morbidity and mortality in kidney transplant recipients. Careful pretransplant screening, immunization, and posttransplant prophylactic antimicrobials may all reduce the risk for posttransplant infections. Chronic immunosuppression, required to maintain allograft function post-organ transplant, predisposes transplant patients to a variety of viral infections....

 Open Access DOI:10.23937/2469-567X/1510039

Prevalence of Haematological and Serum Biochemical Abnormalities in HIV Infected Patients in Ghana, Before and after Antiretroviral Therapy

Samuel Kwadwo Afari and Emmanuel Awusah Blay

Article Type: Research Article | First Published: June 07, 2018

Highly Active Antiretroviral Therapy (HAART) has led to prolonged survival of HIV-infected patients. However, the long-term use of HAART has the potential to cause haematological and biochemical abnormalities such as cytopenia, liver damage and renal injuries, which may be life threatening....

 Open Access DOI:10.23937/2469-567X/1510038

Adherence to Antiretroviral Therapy among Adult Persons Living with HIV/AIDS in Southern Ethiopia

Hailu Chare Koyra

Article Type: Original Research | First Published: 10.23937/2469-567X/1510038

Unlike other chronic diseases, people receiving anti-retroviral treatment should have very high levels of adherence (≥ 95%) to achieve durable suppression of viral load; avoid the emergence of drug resistance and clinical failure. Therefore, this study was aimed to assess level of adherence and predictors of poor adherence among adult ART patients at Dubbo St. Marry Hospital, Southern Ethiopia....

Volume 5
Issue 1