Open Access DOI:10.23937/2469-567X/1510067
Emerging and Re-Emerging Viral Diseases: The Case of Coronavirus Disease-19 (COVID-19)
Gedif Meseret Abebe
Article Type: Review Article | First Published: June 29, 2020
Infectious viral diseases are the never-ending challenge that can emerge or re-emerge in unpredictable regions and at unpredictable times. Human beings are facing an intractable problem in unexpected time and place due to these viral diseases. Human, ecological, and viral related factors are the contributing factors in the emergence or re-emergence of viral infectious disease. Travel, mass gathering, urbanization, fragile or deteriorated health systems, weak disease surveillance system, limited ...
Open Access DOI:10.23937/2469-567X/1510066
Sapling and Handling of COVID-19 Patients in India
Nihar Gupta, Shweta Bahadure, Obaid Noman and Arvind Bhake
Article Type: Review Article | First Published: June 27, 2020
This is a review article on how we can sample the COVID-19 patients, what samples can be obtained, what are the procedures to collect those samples and the precautions some laboratory personnel need to take while processing the samples. This review article mainly focuses on the various methods used in India while sampling COVID-19 patients. For now, RT-PCR is the most reliable test for COVID-19 detection. Few rapid test kits were introduced by ICMR, but now have been withdrawn as they were showi...
Open Access DOI:10.23937/2469-567X/1510065
A Review on Remdesivir: An Alternative Antiviral Drug to Fight against COVID-19
Nimesh Singh, Bharat Suthar, Abhay Mehta, Sandeep Shukla and Archna Pandey
Article Type: Review Article | First Published: June 20, 2020
Coronavirus contamination that was found in mid-2019 has just hampered the world’s motivation up until now. The quantity of irresistible cases has become worldwide to 35 lakhs thus the episode has been portrayed as a pandemic by the planet’s wellbeing association, yet there have not been any “particular medications” or antibodies accessible to date. Applicable reports have distinguished a novel coronavirus with 80% homology. So there are not many signs accessible when different nations a...
Open Access DOI:10.23937/2469-567X/1510064
Vitamin D: A Review and Proposed Evidence for Treatment or Prevention in COVID-19
Nimesh Singh, Bharat Suthar, Abhay Mehta, Sandeep Shukla and Archna Pandey
Article Type: Review Article | First Published: June 20, 2020
WHO declared COVID-19 a worldwide pandemic. The ambitions of this paper are to assess if there is any affiliation between mean levels of diet D in various countries and cases respectively mortality because of COVID-19. Low vitamin D repute in winter allows viral epidemics. During iciness, those who do not take Vitamin D supplements are possibly to have low serum 25-hydroxyvitamin D [25(OH)D] (25-hydroxyvitamin D) concentrations. Vitamin D can reduce the chance of viral epidemics and pandemics in...
Open Access DOI:10.23937/2469-567X/1510063
Prenatal is Still Neglected in Resource-Limited Areas despite the Use of Tests That Optimize the Diagnosis of Infectious Diseases in Brazil
Galileu Barbosa Costa, Raquel Gois Bastos, Ney Cristian Amaral Boa Sorte, Antônio Conceição da Purificação, Beneli Miranda dos Santos, Bernardo Galvão-Castro, Sara Nunez Vaz, Lauro Juliano Marin and Sandra Rocha Gadelha
Article Type: Original Research | First Published: June 05, 2020
Vertically transmitted infections are caused by a diversity of pathogenic microorganisms, and pregnant women are routinely screened to evaluate the risks and reduce the burden of general disorders in their unborn. We assessed the seroprevalence of syphilis, toxoplasmosis, hepatitis B and C, HIV and Human T lymphotropic virus (HTLV) in pregnant women using public healthcare services in two main cities in South region of Bahia State, Brazil. Blood samples were collected using filter paper cards fr...
Open Access DOI:10.23937/2469-567X/1510062
Risky Behaviors among HIV Serodiscordant and Seroconcordant Couples in Yaounde-Cameroon
Constantin Tchakounte, Thibau Flaurant Tchouangueu, Marie Nicole Ngoufack, Leaticia Grace Yatchou, Salomon Tchuandom Bonsi, Jean Olivier Ngono Djang, Etienne Philemon Atabonkeng, Jules-Rogers Kuiate, Alexis Ndjolo and Céline Nkenfou Nguefeu2
Article Type: Original Research | First Published: April 20, 2020
Serodiscordant HIV couples are an important source of HIV spread in sub-Saharan Africa. To limit the transmission of HIV within couples, UNAIDS has defined many strategies, including unconditional treatment of the infected partner, systematic condom use, assisted reproduction, regular screening of the negative partner. In Cameroon, there is little information on the follow up of HIV serodiscordant and seroconcordant couples. The purpose of this work was to describe risky behaviors within serodis...
Open Access DOI:10.23937/2469-567X/1510061
Modified Non-Invasive Computational Methods of HIV Drug Combinations for Treatment of Coronavirus Disease-19 (COVID-19)
Tamer Ezzat Youssef and Youssef Tamer Moustafa
Article Type: Original Research | First Published: April 11, 2020
As of 18 March 2020, more than 191127 cases of confirmed COVID-19 have been documented globally with over 7807 deaths. The impact of COVID-19 on patients with HIV have common presentations like non-HIV patients include fever, dry cough, difficulty of breath. Parallel evidence indicates that the risk of disease increases with critically more than 66 years age, including chronic lung disease. It is very difficult to use drugs on the market. We apply drug design computer techniques to find the expe...
Open Access DOI:10.23937/2469-567X/1510059
Molecular Detection of Human Papilloma Virus Type 16 among Conjunctival Intraepithelial Neoplasia Patients in Khartoum State, Sudan
Hala H Ahmed, Aya A Almtry, Isra M Aidrous, Sara M Ali, Mohamed H Arbab and Ali M Badri
Article Type: Research Article | First Published: February 29, 2020
Many factors like exposure to UV radiation, climatic conditions, genetic predisposition, immunological state and, more recently, the presence of HPV have been implicated in the genesis of some lesions of the conjunctiva, especially the carcinoma. The study was carried out to detect Human Papilloma Viruses HPV type 16 in conjunctival intraepithelial neoplasia patient in Khartoum state, Sudan during the period from March to July 2019. A total of 50 Formalin-fixed paraffin- embedded Samples were co...
