Long-term Maintenance HP Acthar® Therapy for the Treatment of Refractory Idiopathic Membranous Nephropathy
Anushka Chadha, MD and Inderpal Chadha, MD
Article Type: Case Report | First Published: June 11, 2020
Current first-line treatments for idiopathic membranous nephropathy often insufficiently reduce proteinuria and creatinine. Additional treatments options are needed for these refractory cases. Herein, we describe the case of a 68-yearold white male with worsening dyspnea and peripheral lower extremity edema with biopsy-proven membranous nephropathy, without any identifiable secondary causes of the disease. He failed to achieve partial or complete remission after initial therapy of enalapril, ato...
Isolated Renal Mucormycosis in an Immunocompetent Individual
Amit Katyal, Preet Shah and PM Dogra
Article Type: Case Report | First Published: April 16, 2020
Isolated renal mucormycosis is rarely reported in immunocompetent individuals. It carries a grave prognosis and the diagnosis is often achieved post-mortem. We report the case of a 22-year-old immunocompetent gentleman who presented with fever, abdominal pain and renal failure. He was managed with antibiotics, Amphotericin-B and underwent nephrectomy, with a favourable outcome. The case emphasizes that isolated renal mucormycosis may affect immunocompetent individuals. The aggressive nature of d...
Renal Equations Using Cystatin C and Creatinine in Correlation to Lipids in Chronic Kidney Disease - A Cross-Sectional Study
P Ravi Kumar, MD, Mitali Srivastava, MD and S Asmathulla, MD
Article Type: Original Research | First Published: April 15, 2020
This cross-sectional study, comprising of 120 CKD patients, attempted to determine, which of the two equations for estimating GFR, either by serum cystatin-C or by serum creatinine, is better related with lipid profile which is widely portrayed as a cardiovascular risk factor. The parameters evaluated included lipid profile, serum creatinine and serum cystatin-C among others. Staging was done by both the equations (MDRD equation by creatinine and CKD-EPI equation by cystatin-C) and compared, and...
A Case of Cryoglobulinemia after Successful Hepatitis C Virus Treatment
Christopher Farmakis, MD, Victor Canela, DO, Leigh Hunter, MD, FACP, Ravina Linenfelser, DO, Brooke Mills, MD, Kyawt Shwin, MD and Anne R Murray, PhD
Article Type: Case Report | First Published: April 09, 2020
Cryoglobulinemic vasculitis is a complex and destructive disease process that affects multiple organ systems. The pathophysiology includes formation of immune complex deposits that create an inflammatory response in various organs, yielding distinct presentations such as purpura, arthralgias, neuropathy, fever, and pulmonary vasculitis. Over 30% of cryoglobulinemic vasculitis cases present with glomerulonephritis, which carries a worse prognosis. The majority of mixed cryoglobulinemia cases are ...
Incidence, Microbiological Spectrum and Outcomes of Infective Peritonitis in Chronic Peritoneal Dialysis Patients
Vivek Sood, Vivek Kumar, Raja Ramachandran, Shefali Gupta, Vikas Gautam, Manish Rathi, HS Kohli1 and KL Gupta
Article Type: Original Article | First Published: January 20, 2020
Peritoneal dialysis related peritonitis is a major risk factor for drop-out of patients on continuous ambulatory peritoneal dialysis. Data on factors affecting outcome of chronic peritoneal dialysis related peritonitis and microbiology is limited. In this regard, a retrospective, observational study was conducted at Post Graduate Institute of Medical Education and Research, Chandigarh, India, wherein we reviewed medical records of chronic peritoneal dialysis patients for 3 years between 01 July ...