Bullous pemphigoid (BP) is a rare autoimmune subepithelial blistering disease affecting mostly older adults . Studies have calculated an annual incidence ranging from 2.4% to 21.7% per million population. While triggers are found in less than 15% of cases, drugs are well-known trigger factors. Recently, dipeptidyl peptidase-4 inhibitors (DPP4i) have been associated to this condition. Our study presents four cases of older adults with BP associated to the use of DPP4i. The relevance of this study...

To evaluate the utility of the Impact Stratification Score (ISS) in characterizing health-related disease burden for older adult patients with multiple chronic conditions (MCC). The sample of 1226 older adult MCC patients (average age of 80, 51% female, and 89% White) completed the PROMIS-29 v2.1 profile that contains the 9 ISS items. The ISS was examined using factor analysis (i.e., correlated factors and bifactor models)....