Syphilis: A Tricky Disease that may Pose Some Diagnostic Challenges - A Case Report
Norberto Sugaya and Dante Migliari
Article Type: Case Report | First Published: September 24, 2018
This article reports a case of secondary stage syphilis involving the oral mucosa and the skin (the palms). The lesion's clinical aspects of both sites could possibly be misdiagnosed for some common inflammatory diseases, among them oral lichenoid contact lesion or drug reaction. As a standard procedure, the differential diagnosis required to rule out syphilis. The treponemal and anti-treponemal tests confirmed the diagnosis of syphilis. The patient was successfully treated, but, unfortunately, ...
A Review on Sheeppox and Goatpox: Insight of Epidemiology, Diagnosis, Treatment and Control Measures in Ethiopia
Takele Tesgera Hurisa, Zhizhong Jing, Huaijie Jia, Guohua Chen and Xiao-Bing He
Article Type: Review Article | First Published: August 29, 2018
Sheeppox and goatpox are caused by a genus of Capripox virus causing a severe problem and great economic loss in Ethiopia and also in sheep and goat rearing countries in many parts of the world. The objective of this review is to give insight on epidemiology, diagnosis, treatment and control measures of sheeppox and goatpox disease. Generally, the disease is less commonly seen in indigenous breeds in area where it is endemic as compared to exotic breeds. Mostly the disease is transmitted by dire...
Digital Surveillance and Communication Strategies to Infectious Diseases of Poverty Control and Elimination in Africa
Ernest Tambo, Shang Xia, Xin-Yu Feng and Zhou Xiao-Nong
Article Type: Review Article | First Published: August 23, 2018
Investing in digital technologies to support health-based research, modelling and planning, preparedness and timely effective response, and long-term management benefits has been recognized in improving epidemiological analysis, disease prevention, control to elimination, health education and promotion. This paper provides valuable insights and approaches for public health in collection, analysis, interpretation, use and dissemination of health surveillance data, resource allocation, for guiding...
Cerebro-Meningeal Tuberculosis in HIV-Negative Adults
Guenifi Wahiba, Gasmi Abdelkader, Boukhrissa Houda, Rais Mounira, Hachani Abderahmen, Ouyahia Amel, Mechakra Saleh and Lacheheb Abdelmadjid
Article Type: Research Article | First Published: July 26, 2018
Tuberculosis remains a public health problem worldwide. Neurological localization is the most severe manifestation of extra-pulmonary tuberculosis characterized by a high mortality rate and a high rate of sequelae among survivors; its diagnosis is hampered by the absence of rapid and accurate tools, therefore it is often evoked and treated on presumption arguments. The aim of this study is to assess the epidemiological, clinical, diagnostic, treatment, and outcome features in patients with cereb...
New Perspectives of HCV Infection: Focus on New Treatment Agents and Comorbidity Status, a Short Review
Huang Yu-Fen and Su Hui-Chen
Article Type: Short Review | First Published: July 23, 2018
Chronic hepatitis C (CHC) is one of the main leading causes of mortality associated with liver disease worldwide. Different predominant modes of transmission in the local area play an important role for the disease burden. Several cofactors are identified to accelerate the disease progression. Besides, several comorbidities are common in patients with CHC and also have poor response to the traditional combination of pegylated interferon and ribavirin (PegIFN/RBV) treatment....
Common Pathophysiological Pathways for Apical and Upper Lobe Lung Disease
Aaron R Casha, Alexander Manche, Marilyn Gauci, Andre Navarro and Emanuel Farrugia
Article Type: Review Article | First Published: July 20, 2018
The pathophysiological factors that make the upper lobe "vulnerable" to various different pathologies are additive, and not mutually exclusive. They include a tall, thin body habitus with an antero-posteriorly flattened chest as associated with a low BMI, compounded by the poor apical blood supply and concomitant limited lymphatic drainage, possibly accentuated by a physically tall lung and a deep first rib furrow that makes the apex appear prominent....