Evaluation of Cases with Gemella Infection: Cross-Sectional Study
Selcuk Nazik, Esma Cingoz, Ahmet Riza Sahin and Selma Ates
Article Type: Original Article | First Published: December 19, 2018
Gemella is a Gram-positive, catalase-negative, facultatively anaerobic coccus bacterium. It is a member of the normal flora and rarely causes infection. This study aims at evaluating, accompanied by the literature, Gemella-associated infections that are also present in the normal flora. This study is a cross-sectional study. Gemella infections recorded in 2014-2018 in University Hospital, Turkey. Gemella is a Gram-positive, catalase-negative, facultatively anaerobic coccus bacterium. It is parti...
Clostridium difficile in Autologous Hematopoietic Stem Cell Transplant Patients
Jennifer E MacDonald, Ashley E Glode and Luciano J Costa
Article Type: Research Article | First Published: December 15, 2018
Diarrhea is a common complication of hematopoietic stem cell transplant (HSCT) due to multiple etiologies, including toxicity from the conditioning regimen and Clostridium difficile (C. difficile) infection. We hypothesized that C. difficile infection is uncommon in recipients of autologous HSCT (auto-HSCT) and testing for C. difficile is over utilized at our institution. We performed a retrospective, single center analysis of the use of polymerase chain reaction (PCR) testing for C. difficile a...
Tigecycline Induced Cholestatic Liver Injury: A Case Report
Jing Liang, Kai Zhao, Liqin Zhu and Yihe Liu
Article Type: Case Report | First Published: November 26, 2018
A 41-year-old female patient received tigecycline because of abdominal infection caused by carbapenem-resistant klebsiella pneumoniae (CRKP) after performing cholangiolithotomy by the endoscopic retrograde cholangio-pancreatography (ERCP). Subsequently she developed cholestatic liver injury as substantiated by increased alkaline phosphatase (ALP) and bilirubin. Tigecycline was switched to dual carbapenems. Her liver function tests improved. We suggest that bilirubin levels should be cared in pat...
Patient-Centered MDR-TB Care: What do MDR-TB Patients in Urban and Rural Peru Say?
Sangeeta Mookherji and Kei Alegria-flores
Article Type: Research Article | First Published: November 05, 2018
Controlling multidrug and extremely drug-resistant tuberculosis (M/XDR-TB) poses a grave challenge to public health, globally. Studies repeatedly show that effective M/XDR-TB management goes beyond strategies recommended in global TB control plans, uniformly pointing to patient-centred care as critical to progress in controlling the epidemic. We aim to describe patient-centred care in M/XDR-TB management in Peru, which presented a context where M/XDR-TB remains a persistent problem, even with in...