Journal of

Musculoskeletal Disorders and TreatmentISSN: 2572-3243


 Open Access DOI:10.23937/2572-3243.1510037

Molecular Changes at the Post-Synapse and Improved Motor Function Suggest Accelerated Recovery with SARM Treatment in an Androgen-Depleted Animal Model of Nerve Injury

John Bryant, James MacKrell, David Gifondorwa, Benjamin Yaden, Bethany Monroe, Kimberly Tyler, Joshua Davis, Alexander Culver, Pamela Shetler, Prabhakar Jadhav, Henry Bryant and Venkatesh Krishnan

Article Type: Research Article | First Published: June 22, 2017

Nerve crush injury at focal sites causes rapid muscle atrophy in the connected muscle downstream of the affected motor end plate, and results in profound functional and metabolic deficits. This report characterizes the resultant functional and molecular changes at the post-synapse in an androgen depleted mouse model of reversible nerve injury....

 Open Access DOI:10.23937/2572-3243.1510036

Floating First Metacarpal: Fracture Dislocation of the Trapezio-Metacarpal Joint Associated with Fracture of the Base of the Proximal Phalanx: A Case Report

Hamdi Kaziz, Thabet Mouelhi, Walid Osman, Nader Naouar and Mohamed Laziz Ben Ayeche

Article Type: Case Report | First Published: June 21, 2017

Floating first metacarpal has been scarcely described in the literature. Fracture dislocation of the trapezio-metacarpal joint has been reported more than the isolated form but deemed exceptional....

 Open Access DOI:10.23937/2572-3243.1510035

Minimally Invasive Percutaneous Screw Fixation of Phalangeal Fractures of the Hand

Simon-Perez C, Garcia-Virto V, Garcia-Medrano B, Rodriguez-Mateos JI, Faour-Martin O and Martin-Ferrero MA

Article Type: Research Article | First Published: June 01, 2017

This study present the results of an effective, minimally invasive treatment method for displaced diaphyseal and articular fractures of hand phalanges, which are difficult to manage and frequently involve complications stemming from excessive treatment....

 Open Access DOI:10.23937/2572-3243.1510034

Acute Lymphoblastic Leukemia in Systemic Lupus Erythematosus Disguise: A Case Report

Gaafar Ragab, Hala El-Gendy and Rasmia M El-Gohary

Article Type: Case Report | First Published: June 08, 2017

The present report describes the case of an 18-year-old male exhibiting Acute Lymphocytic Leukemia (ALL). He initially presented with a multitude of rheumatic manifestations that were attributed to Systemic Lupus Erythematosus (SLE). The initial peripheral smear and bone marrow exam did not show any abnormal cells that developed later on along his disease course....

 Open Access DOI:10.23937/2572-3243.1510033

Entrapment of the Common Peroneal Nerve due to Multiple Hereditary Exostoses with Synostosis of the Proximal Tibiofibular Joint

Ingo Schmidt

Article Type: Short Communication | First Published: May 19, 2017

A 37-year-old male presented with progredient weakness of dorsiflexion in his left ankle since 5 months that was accompanied with sensory deficits in the superficial peroneal nerve area at the dorsal aspect of his left foot. Additionally, the patient reported increasing pain around his left Proximal Tibiofibular Joint (PTFJ). There was a history of known Multiple Hereditary Exostoses (MHE) that was primarily diagnosed with patient's age of 8 years....

 Open Access DOI:10.23937/2572-3243.1510032

Is Bony Evidence of Enthesial Reaction Sufficient for Differential Diagnosis?

Bruce Rothschild

Article Type: Research Article | First Published: May 10, 2017

Enthesial reaction, as a stress or disease marker, has been a generalized perspective, largely untested as to its veracity. Perhaps valid with soft tissue visualization by computerized tomography or magnetic resonance imaging, examination of standard radiographs reveals minimal evidence of enthesial reaction. The current study seeks to assess the disease-specificity of enthesial reaction by examining the primary evidence that of disease-related variation in its presence in defleshed skeletons......

Volume 3
Issue 2