Journal of

Rheumatic Diseases and TreatmentISSN: 2469-5726

Archive

 Open Access DOI:10.23937/2469-5726/1510022

Lupus-Associated Pancreatitis: Clinical Aspects

Maria Helena Favarato

Article Type: Review Article | First Published: September 28, 2015

Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease, with several different clinical manifestations. Its annual incidence is about 5 cases per 100000 inhabitants. The prevalence is around 52 cases per 100000 inhabitants. The gastrointestinal tract may be affected, either by the disease itself or by adverse reactions of medications or by opportunistic infections. Although common, the incidence of gastrointestinal manifestations may be underestimated, as the symptoms m...

 Open Access DOI:10.23937/2469-5726/1510021

Eosinophilic Fasciitis Treated with Tocilizumab: Demonstration of Efficacy after Withdrawal and Re-Challenge in a Patient

Glen T D Thomson, Janine L Johnston and Brent R J Thomson

Article Type: Case Report | First Published: September 28, 2015

A 41-year-old man presented with clinical features of eosinophilic fasciitis (EF) confirmed on biopsy. The patient responded to high-dose prednisone but subsequent steroid sparing medication including methotrexate, hydroxychloroquine, etanercept, golimumab and rituximab failed to deliver steroid sparing response. Tocilizumab provided rapid and sustained improvement in the patient's symptoms and signs. Withdrawal of tocilizumab resulted in a flare of the clinical manifestations of EF; retreatment...

 Open Access DOI:10.23937/2469-5726/1510020

A Case of Rhabdomyolysis and Polyarticular Inflammatory Arthritis May be the Initial Presentation of Chronic Myelogenous Leukemia (CML)

Yelliann Ruiz-Irizarry and Petros Efthimiou

Article Type: Case Report | First Published: September 24, 2015

Rhabdomyolysis and inflammatory arthritis are common rheumatologic conditions that manifest in people of all ages. Proximal muscle weakness associated to rhabdomyolysis is frequently the initial presentation of inflammatory myopathies such as dermatomyositis (DM) and polymyosistis (PM) both, extensively described in literature to be related to paraneoplastic process. Inflammatory arthritis has been associated to certain paraneoplastic syndromes, but not in relation to Chronic Meylogenous Leukemi...

 Open Access DOI:10.23937/2469-5726/1510019

A MRI Assessment of the Response of Chronic, Occult, Synovial-Based Inflammation of Gout to Serum Urate Lowering Therapy

John D. Carter, Michelle Patelli, Scott R. Anderson, Neelesh Prakash, Ernesto J. Rodriquez and Louis R. Ricca

Article Type: Research Article | First Published: September 09, 2015

Clinical gout begins as an acute intermittent and intensely painful arthritis that can progress to a chronic, inflammatory, destructive condition. The initial episodes may last several days and are often followed by pain-free, inter-critical periods that may last months to years. Chronic gouty arthritis is manifested by shorter inter-critical periods, boney destructive changes and possible development of visible tophi. Advanced gout leads to chronic pain, decreased quality of life, and an increa...

 Open Access DOI:10.23937/2469-5726/1510018

A Flowchart For Understandıng Ankylosing Spondylitis Management Recommendatıons of Asas/Eular

Nihal Ozaras

Article Type: Letter | First Published: August 03, 2015

Ankylosing spondylitis (AS) is one of the most frequently seen rheumatic diseases in clinical practice. Its treatment is defied by the Assessment of SpondyloArthritis international Society (ASAS)/ European League Against Rheumatism (EULAR). A flowchart is designed to easily understand this treatment strategy....

 Open Access DOI:10.23937/2469-5726/1510017

Pathological Relationship of Osteomalacia at the Site of Atypical Periprosthetic Femoral Shaft Fracture after Typical Femoral Neck Fracture Occurred in the Patient with Rheumatoid Arthritis: A Case Report

Takanori Wakayama, Yoshitomo Saita, Tomonori Baba, Hidetoshi Nojiri and Kazuo Kaneko

Article Type: Case Report | First Published: July 17, 2015

We describe a patient who suffered an atypical periprosthetic femoral shaft fracture two years after surgical treatment for a typical osteoporotic femoral neck fracture. This patient had been suffering from rheumatoid arthritis (RA), steroid-induced diabetes, and steroid-induced osteoporosis, and had undergone long term administration of glucocorticoids (GCs), bisphosphonates (BPs), and active vitamin D (aVD) analog. Prodromal pain and periprosthetic cortical stress reaction had occurred in the ...

 Open Access DOI:10.23937/2469-5726/1510016

A Case of Malignant Malaria Complicated By Symmetrical Peripheral Gangrene

Amira A Shahin, Noha M Abdelbaky and Sahar S Emam

Article Type: Case Report | First Published: July 09, 2015

Symmetrical peripheral gangrene (SPG) is a rare complication of malaria. The ischemic changes begin distally and progress rapidly to cause irreversible tissue necrosis requiring amputation in almost all cases. We report a case of a 21-years-old female with malignant malaria complicated by SPG. Our treatment regimen includes corticosteroids in addition to the anti-malaria and anticoagulation therapy. Clinicians should be aware of this entity as early recognition can help in reducing morbidity and...

 Open Access DOI:10.23937/2469-5726/1510015

Anxiety and its Impact on Osteoarthritis Pain: An Update

Prof. Ray Marks

Article Type: Review Article | First Published: July 03, 2015

Anxiety is a very common psychological syndrome occurring in the adult population either as a trait or specific condition, and/or in response to a variety of situations, especially adverse health conditions. This narrative review examines the extent to which anxiety may preside among adults with a diagnosis of osteoarthritis, regardless of site, and its linkage to the pain experience. Drawn from the English language peer reviewed work over the last 35 years, articles that focused on the topic of...

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