Journal of

Rheumatic Diseases and TreatmentISSN: 2469-5726

Archive

 Open Access DOI:10.23937/2469-5726/1510052

Rheumatoid Arthritis of the Craniovertebral Junction: Surgical Strategies, Current Approach and Proposal of a New Therapeutic Algorithm

Luis Eduardo Carelli Teixeira da Silva, Alderico Girao Campos de Barros and Marcelo Glauber da Silva Pereira

Article Type: Review Article | First Published: June 12, 2017

Rheumatoid Arthritis (RA) is a systemic inflammatory disease with an autoimmune feature and an etiology that is still unknown. It is characterized by a symmetrical peripheral polyarthritis that affects primarily the small joints of hands and feet, with several levels of extra-articular manifestation....

 Open Access DOI:10.23937/2469-5726/1510051

A Pediatric Case of NMOSD with Positive Seroconversion of AQP4-ab after 5 Years and Subsequent Diagnosis of SLE

Aisha Bushra, Osman Farooq, Svetlana P Eckert, Caila B Vaughn, Rabheh Abdul Aziz and Bianca Weinstock-Guttman

Article Type: Case Report | First Published: March 18, 2017

Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating disorder of the central nervous system that is distinct from multiple sclerosis and is primarily characterized by recurrent episodes of optic neuritis (ON) and/or longitudinal extensive transverse myelitis (LETM). The presence of aquaporin antibodies (AQP4-ab) in the serum and/or cerebrospinal fluid (CSF) is a highly specific biomarker for diagnosis, although repeated testing may be necessary to confirm its presence....

 Open Access DOI:10.23937/2469-5726/1510050

Role of Strontium Ranelate in the Therapy of Osteoporosis

Pavel Horak, Martina Skacelova and Ahmed Kazi

Article Type: Review Article | First Published: March 01, 2017

Strontium ranelate is a medicine used to treat postmenopausal osteoporosis in women and osteoporosis in men. Preclinical data suggest its dual effect consisting of the control of bone resorption and promotion of bone formation. Administration of strontium ranelate leads to significant increase in the bone mass. Changes in bone density can be used to evaluate the adherence of patients as well as, in case of strontium ranelate, to estimate the fracture risk reduction....

Volume 3
Issue 2