Table 1: Clinical laboratory results throughout duration in the Intensive Care Unit.

Illness Day/

Admission Day

Reference Range

Day 7/

Day 1

Day 8/

Day 2

Day 9/Day 3

Day 10/

Day 4

Day 11/

Day 5

Day 12/

Day 6

Day 13/

Day 7

Day 14/

Day 8

Day 15/

Day 9

Day 16/

Day 10

Day 17/

Day 11

Day 18/

Day 12

Hemoglobin (g/L)

135-175

139

130*

118*

116*

111*

120*

121*

119*

116*

126*

107*

106*

Leukocyte (per µL)

4,00-11,000

6,500

6,200

3,900*

6,300

8,400

8,500

7,600

8,400

8,800

14,200

9,600

10,200

Absolute Neutrophil (per µL)

2,000-7,500

5,300

4,600

3,000

5,200

7,100

7,100

5,100

6,300

5,700

10,500

6,200

6,600

Absolute Lymphocyte (per µL)

1,000-3,500

700*

1,200

500*

400*

500*

300*

1,100

700*

1,300

2,500

1,700

2,000

Neutrophil: Lymphocyte Ratio

----

7.54

3.83

6

13

14.2

23.7

4.64

9

4.38

4.2

3.65

3.3

Platelet (x1000 per µL)

150-400

181

163

150

170

188

234

257

281

283

364

257

229

Sodium (mmol/L)

135-147

130*

134*

132*

136

138

134*

135

133*

134*

133*

137

135

Potassium (mmol/L)

3.5-5.2

5

4

5.2

4.6

4.5

4.6

3.8

5.1

4.2

4.3

3.8

3.6

Chloride (mmol/L)

95-110

96

98

97

99

101

98

97

94

95

96

98

97

Carbon Dioxide (mmol/L)

23-34

26

27

24

22*

23

21*

21*

19*

23

19*

22*

22*

Anion Gap (mmol/L)

May-15

8

9

11

15

14

15

17*

20*

16*

18*

17*

16*

Creatinine (µmol/L)

58-110

163*

210*

469*

512*

558*

660*

613*

825*

694*

794*

683*

611

Albumin (g/L)

35-50

26*

25*

23*

23*

----

----

24*

25*

----

25*

----

----

Calcium (mmol/L)

2.12-2.52

2.07*

1.94*

1.86*

1.92*

1.88*

2.01*

2.18

2.09*

2.02*

2.01*

2.17

2.24

Magnesium (mmol/L)

0.74-1.00

0.88

0.83

1

0.92

0.87

1

0.94

1.12

0.91

1.03*

0.93

0.81

Phosphorus (mmol/L)

0.80-1.45

1.61*

1.07

1.85*

2.05*

2.19*

2.79*

2.18*

3.93*

3.37*

3.14*

2.68*

2.54*

Glucose (mmol/L)

3.6-6.9

21.3*

16.5*

24.0*

19.7*

14.9*

15.0*

12.5*

9.9*

----

----

5.6

7.0*

Lactate (mmol/L)

0.4-2.1

1.3

---

0.9

1.1

0.7

----

1.1

----

----

----

----

----

INR

0.8-1.2

---

---

1.1

1

1

----

1

1

----

----

----

----

Arterial pH

7.35-7.45

7.19*

7.37

7.18*

7.20*

7.16*

7.26*

7.27*

7.23*

7.26*

7.26*

7.30*

7.37

Arterial pCO2 (mmHg)

35-45

84*

40

54*

61*

66*

49*

45

47*

49*

44

45

39

Arterial pO2 (mmHg)

80-100

70*

81

66*

70*

61*

110

70*

82

126

76*

78*

87

Arterial HCO3 (mmol/L)

22-26

32*

23

20*

20*

20*

20*

20*

18*

20*

19*

21*

22

AST (u/L)

Oct-40

----

----

----

----

----

----

----

30

----

----

----

----

ALT (u/L)§

May-68

----

----

----

----

----

----

----

47

----

----

----

----

ALP (u/L)||

50-136

----

----

----

----

----

----

----

100

----

----

----

----

Bilirubin (µmol/L)

Mar-22

----

----

----

----

----

----

----

6.9

----

----

----

----

D-Dimer (u/mIFEU) **

< 0.5

----

0.9*

----

----

----

----

----

> 10.0*

----

----

----

----

Lactate Dehydrogenase (u/L)

84-246

----

----

----

----

----

----

----

299*

----

----

269*

----

C-Reactive Protein (mg/L)

< 2.90

----

----

----

----

----

----

----

42.96*

----

----

----

----

Ferritin (µg/L)

28-388

----

----

----

----

----

----

----

746*

----

----

----

----

*: Abnormal values; INR: International Normalized Ratio; AST: Aspartate Aminotransferase; §ALT: Alanine Aminotransferase; ||ALP: Alkaline Phosphatase; **IFEU: Fibrinogen Equivalent Unit. The most abnormal results of each day were reported in this table.