Table 2: Mean QTc during four years for patients in MMT.
|
|
Sample size |
QTc interval (ms) |
QTc normala |
QTc prolongateda |
QTc dangerously prolongateda |
|
T0 without methadone use |
40 |
415.8 ± 23.0 |
38 (95.0) |
2 (5.0) |
0 |
|
T0 with methadone use |
262 |
429.4 ± 25.9 |
210 (80.2) |
50 (19.1) |
2 (0.8) |
|
T1 |
174 |
430.1 ± 25.8 |
143 (82.2) |
28 (16.1) |
3 (1.7) |
|
T2 |
159 |
434.9 ± 25.7 |
122 (76.7) |
36 (22.6) |
1 (0.6) |
|
T3 |
126 |
436.8 ± 28.6 |
93 (73.8) |
30 (23.8) |
3 (2.4) |
|
T4 |
112 |
431.4 ± 25.0 |
96 (85.7) |
14 (12.5) |
2 (1.8) |
Numbers are mean ± standard deviation or number (%); aThe QTc interval was divided into three categories; normal (< 450 ms for males and < 460 ms for females), prolonged (≥ 450 -< 500 ms for males and ≥ 460 -< 500 ms for females), and dangerously prolonged (≥ 500 ms for males and females).