Table 5: The toxicity profiles of the lead compounds.

Compounds

LD50 (mg/kg)

TC

CG

HT

MG

CT

IT

PA

C1

900

4

-

-

-

-

-

100

C2

900

4

-

-

-

-

-

100

C3

1320

4

-

-

-

-

+

69.26

C4

2000

4

-

-

-

-

-

68.07

C5

2500

5

-

-

-

-

+

70.97

C6

23000

6

-

-

-

-

-

67.38

C7

150

3

-

-

-

-

+

69.26

C8

6060

6

-

-

-

-

-

67.38

C9

2000

4

-

-

-

-

-

68.07

C10

2000

4

-

-

-

-

-

70.97

C11

150

3

-

-

-

-

+

69.26

C1 = Myristic Acid, C2 = Palmitic Acid, C3 = Xanthinin, C4 = 2,3-Dehydro-4-oxo-beta-ionol, C5 = Coniferyl alcohol, C6 = alpha-D-glucopyranoside, C7 = Ambrosiol, C8 = 2,3,5,5,8a-pentamethyl-6,7,8,8a-tetrahydro-5H-chromen-8-ol, C9 = (7E)-2,6,6-Trimethyl-3-methylene-7-(3-oxobutylidene) oxepanyl acetate, C10 = (8S,14)-cedran-diol, C11 = 3-oxo-10(14)-epoxyguai-11(13)-en-6,12-olide.
Key: TC: Toxicity class; CG: Carcinogenicity; HT: Hepatotoxicity; MG: Mutagenicity; CT: Cytotoxicity; IT: Immunotoxicity; PA: Prediction accuracy (%)