Table 1: Literature with differing clinical courses.
Author |
Year published |
Age |
Site |
Symptoms duration |
Lesion description |
Size |
Stage at presentation |
Treatment |
Follow-up period |
Outcome |
|
Current study |
2018 |
64 |
Labium minorum |
12 months |
Exophytic lesion |
2 × 1.5 cm |
Stage I |
Wide local excision |
25 months |
No recurrence |
|
Thakur, et al. [5] |
2017 |
55 |
Right vulva |
NR |
Multiple nodulo- ulcerative lesions |
2.5 × 2 cm, 1 × 1.5 cm, 1 × 1.5 cm |
Metastasis to right inguinal LN |
Radiotherapy |
NR |
NR |
|
Sullivan, et al. [8] |
2016 |
76 |
NR |
NR |
Asymptomatic papule |
5 × 3 mm |
Stage I |
Local excision with left ILND |
10 months |
No recurrence |
|
Pusiol, et al. [7] |
2011 |
51 |
Labium majorum |
6 months |
Exophytic lesion |
2.5 × 1.5 cm |
Stage I |
Tumor excision |
18 months |
No recurrence |
|
Khan, et al. [6] |
2003
|
49 |
Labium majorum
|
NR
|
Papilloma-like |
5 mm
|
Metastasis to inguinal LN
|
Wide local excision with bilateral ILND Laparotomy with PLND |
7 months |
Recurrence |
|
Escalonilla, et al. [3] |
1999 |
76 |
Labium majorum |
4 months |
Exophyitic red and white nodule Associated with Bowen’s disease |
4 × 3 cm |
NR |
Adjuvant radiotherapy Excision biopy Radical vulvectomy with bilateral ILND |
12 months |
No recurrence |
|
Carlson, et al. [10] |
1996 |
46 |
Labium majorum |
NR |
Sebaceous cyst-like Pruritic |
NR |
Stage I |
Left radical hemivulvectomy with left ILND |
31 months |
No recurrence |
|
Kawamoto, et al. [2] |
1995 |
78 |
Labium minorum |
6 months |
Yellowish white nodule |
2.5 × 1.5 cm |
Metastasis to left inguinal LN |
Simple vulvectomy with left ILND. Adjuvant radiotherapy |
17 months |
No recurrence |
|
Jacobs, et al. [4] |
1986 |
89 |
Vulva |
12 months |
Pink white plaques |
|
|
||||
Ikuse, et al [11] |
1976 |
|
Labium majorum |
NR |
Red ulcerated tumor |
4 × 4 cm |
Metastasis to the lungs |
NR |
No recurrence |
Demise |
|
Rulon, et al. [9] |
1974 |
31 |
Labium minorum |
6 months |
Raw, yellow, slightly indurated plaque |
2 × 1.1 × 0.3 cm |
NR |
Excision |
13 years 7 months |
No recurrence |
NR: Not Reported; LN: Lymph Node; ILND: Inguinal Lymph Nodes Dissection, PLND: Pelvic Lymph Nodes Dissection.