Table 1: Literature with differing clinical courses.

Author

Year published

Age

Site

Symptoms duration

Lesion description

Size

Stage at presentation

Treatment

Follow-up period

Outcome

Current study

2018

64

Labium minorum

12 months

Exophytic lesion

2 × 1.5 cm

Stage I

Wide local excision

25 months

No recurrence

Thakur, et al. [5]

2017

55

Right vulva

NR

Multiple nodulo- ulcerative lesions

2.5 × 2 cm,

1 × 1.5 cm,

1 × 1.5 cm

Metastasis to right inguinal LN

Radiotherapy

NR

NR

Sullivan, et al. [8]

2016

76

NR

NR

Asymptomatic papule

5 × 3 mm

Stage I

Local excision with left ILND

10 months

No recurrence

Pusiol, et al. [7]

2011

51

Labium majorum

6 months

Exophytic lesion

2.5 × 1.5 cm

Stage I

Tumor excision

18 months

No recurrence

Khan, et al. [6]

2003

 

49

Labium majorum

 

NR

 

Papilloma-like

5 mm

 

Metastasis to inguinal LN

 

Wide local excision with bilateral ILND Laparotomy with PLND

7 months

Recurrence

Escalonilla, et al. [3]

1999

76

Labium majorum

4 months

Exophyitic red and white nodule Associated with Bowen’s disease

4 × 3 cm

NR

Adjuvant radiotherapy Excision biopy Radical vulvectomy with bilateral ILND

12 months

No recurrence

                   

Carlson, et al. [10]

1996

46

Labium majorum

NR

Sebaceous cyst-like Pruritic

NR

Stage I

Left radical hemivulvectomy with left ILND

31 months

No recurrence

Kawamoto, et al. [2]

1995

78

Labium minorum

6 months

Yellowish white nodule

2.5 × 1.5 cm

Metastasis to left inguinal LN

Simple vulvectomy with left ILND. Adjuvant radiotherapy

17 months

No recurrence

Jacobs, et al. [4]

1986

89

Vulva

12 months

Pink white plaques

 

 

     

Ikuse, et al [11]

1976

 

Labium majorum

NR

Red ulcerated tumor

4 × 4 cm

Metastasis to the lungs

 NR

No recurrence

Demise

Rulon, et al. [9]

1974

31

Labium minorum

6 months

Raw, yellow, slightly indurated plaque

2 × 1.1 × 0.3 cm

NR

 Excision

13 years

7 months

No recurrence

NR: Not Reported; LN: Lymph Node; ILND: Inguinal Lymph Nodes Dissection, PLND: Pelvic Lymph Nodes Dissection.