Table 1: Drug interaction between COVID-19 therapy and rate and rhythm controlling agents.
Drug Interaction |
Rate Control Agent |
Rhythm Control Agent |
Hydroxychloroquine/chloroquine [5] |
Digoxin Beta blocker CCB Digoxin |
Amiodarone Flecainide Ibutlide |
Azithromycin [5] |
Digoxin Amiodarone Beta blocker CCB Digoxin |
Flecainide Amiodarone Sotalol Ibutilide |
Lopinavir/ritonavir [5] |
Digoxin Beta blocker CCB Digoxin |
Flecainide Ibutilide Sotalol Dofetilide DCCV |
Fingolimod [5] |
Digoxin Beta blocker CCB |
Flecainide Ibutilide Dofetilide DCCV |
CCB: Calcium Channel Blocker; DCCV: Direct Current Cardioversion