n (%) or median [IQR]

n (%) or median [IQR]

Onset of symptoms and hospital admission (days)

7.0 [4.0-9.5]

Pharmacological treatments

Oxygen supplementation

Antibiotic (except azithromycin)

359 (79.7)

Nasal catheter (NC)

247 (55.5)

Azithromycin

340 (75.0)

Hudson mask

86 (19.3)

Corticosteroid

283 (61.9)

Noninvasive ventilation (NIV)

76 (17.0)

Anticoagulant^*

138 (31.8)

High flow nasal cannula (HFNC)

62 (13.9)

Antiviral (oseltamivir)

130 (29.6)

Mechanical ventilation (MV)

97 (21.1)

Hydroxychloroquine

115 (25.1)

Oxygen therapy combination

Convalescent plasma

76 (16.5)

NC → Hudson mask

79 (17.7)

Vasopressor

69 (15.7)

NC → Hudsonmask → NIV

48 (10.8)

Anti-IL6 drugs (tocilizumab)

12 (2.6)

NC → Hudsonmask → NIV → HFNC

26 (5.8)

Azithromycin + Corticosteroid

116 (25.6)

NC → Hudsonmask → NIV → HFNC → MV

23 (5.1)

Azithromycin + Corticosteroid + Anticoagulant

78 (17.2)

Intensive care unit (ICU)

136 (29.6)

Outcomes

ICU length of stay (days)

15.1 [7.1-29.5]

Hospital discharge

398 (86.7)

With MV

25.2 [11.1-37.0]

Death

40 (8.7)

Without MV

7.2 [5.3-10.5]

Censored^**

21 (4.5)