Table 1: Intestinal permeability of quaternary halomethylated ammonium iodide (C6I).
Solution | Parameter | Mean ± SD |
Saturated | ka (h-1) | 2.10 ± 0.4 |
Papp (cm/s) | 5.10 × 10-5 ± 1.0 | |
r2 | 0.98 ± 0.01 | |
1/10 diluted | ka (h-1) | 1.90 ± 0.37 |
Papp (cm/s) | 4.80 × 10-5 ± 0.9 | |
r2 | 0.98 ± 0.005 |
Notes: With diluted solution only 6 animals were tested.
Abbreviations: ka: Rate constant for absorption of the compound; Papp: Permeability value; r2: Correlation coefficient.