Table 2: Up-regulated annotated genes in Pa CMC-115.
Locus_tag |
Microarray Fold Ratio |
RNA-Seq Fold Ratio |
Gene Name |
Product |
Common Pathways/Functional Classifications |
PA0705 |
8.48 |
∞ |
migA |
Alpha-1,6-rhamnosyltransferase |
Quorum sensing/Cell wall/LPS/capsule/Putative enzymes |
PA0723 |
4.79 |
4.94 |
coaB |
Phage coat protein B |
Related to phage/Transposon/or Plasmid |
PA0745 |
4.3 |
2.6 |
dspL |
|
Enoyl-CoA hydrastase |
PA0958 |
8.36 |
95.89 |
oprD |
Porin D |
Two-component system/beta-Lactam resistance/Transport of small molecules |
PA1092 |
84.71 |
41.35 |
fliC |
B-type flagellin |
Flagella assembly/Two-component system /Motility & Attachment |
PA1093 |
9.35 |
∞ |
flaG |
Hypothetical protein |
Flagella assembly/Hypothetical, unclassified, unknown |
PA1094 |
16.02 |
∞ |
fliD |
B-type flagellar hook-associated protein |
Flagella assembly/Cell wall/LPS/capsule/Motility & Attachment |
PA1095 |
79.61 |
∞ |
fliS |
B-type flagellar protein |
Flagella assembly |
PA1135 |
4.4 |
3.0 |
yedU |
|
Molecular chaperone HSP31/glyoxalase |
PA1317 |
4.78 |
14.80 |
cyoA |
Cytochrome o ubiquinol oxidase subunit II |
Metabolic pathway/Energy metabolism |
PA1902 |
5.07 |
4.95 |
phzD2 |
Phenazine biosynthesis protein |
Quorum sensing/Phenazine biosynthesis/Secreted Factor |
PA1903 |
4.80 |
5.17 |
phzE2 |
Phenazine biosynthesis protein |
Quorum sensing/Phenazine biosynthesis/Secreted Factor |
PA1904 |
4.90 |
5.09 |
phzF2 |
Trans-2,3-dihydro-3-hydroxyanthranilate isomerase |
Quorum sensing/Phenazine biosynthesis/Secreted Factor |
PA2246 |
4.3 |
2.4 |
bkdR |
|
Bkd operon transcriptional regulator BkrD |
PA2329 |
7.51 |
10.35 |
ABC transporter ATP-binding protein |
Transport of small molecules |
|
PA2365 |
5.82 |
5.84 |
hsiB3 |
Hypothetical protein |
Biofilm formation/T6SS/Bacterial secretion system |
PA2366 |
8.20 |
6.36 |
hsiC3 |
Uricase |
Biofilm formation/T6SS/Bacterial secretion system |
PA2367 |
6.75 |
8.36 |
hcp3 |
Hypothetical protein |
Biofilm formation/T6SS/Bacterial secretion system |
PA2368 |
7.51 |
8.18 |
hsiF3 |
Hypothetical protein |
T6SS/Hypothetical, unclassified, unknown |
PA2385 |
5.62 |
20.24 |
pvdQ |
Acyl-homoserine lactone acylase |
Pyoverdine synthesis/Adaptation, Protection |
PA2393 |
13.99 |
17.21 |
pvdM |
Dipeptidase |
Pyoverdine synthesis/Central intermediary metabolism |
PA2394 |
13.71 |
17.97 |
pvdN |
Pyoverdine biosynthesis protein |
Pyoverdine synthesis/Adaptation, Protection |
PA2395 |
4.12 |
34.60 |
pvdO |
Pyoverdine biosynthesis protein |
Pyoverdine synthesis/Adaptation, Protection |
PA2404 |
9.09 |
5.09 |
fpvH |
Hypothetical protein |
Membrane protein |
PA2405 |
6.08 |
7.27 |
fpvJ |
Hypothetical protein |
Hypothetical, unclassified, unknown |
PA2406 |
4.56 |
4.46 |
fpvK |
Hypothetical protein |
Hypothetical, unclassified, unknown |
PA2407 |
4.04 |
5.56 |
fpvC |
Adhesion protein |
ABC transporters/Motility & Attachment/Transport of small molecules |
PA2444 |
5.59 |
5.50 |
glyA2 |
Serine hydroxymethyl transferase |
Biosynthesis of secondary metabolites/Amino acid biosynthesis and metabolism |
PA2445 |
8.46 |
8.25 |
gcvP2 |
Glycine dehydrogenase |
Biosynthesis of secondary metabolites/Amino acid biosynthesis and metabolism/Central intermediary metabolism |
PA2564 |
17.07 |
30282.00 |
tam |
Trans-aconitate 2-methyltransferase |
Hypothetical, unclassified, unknown |
|
|
|
|
|
|
PA2688 |
4.6 |
3.5 |
pfeA |
|
Ferric enterobactin receptor |
PA4078 |
5.29 |
7.94 |
Probable nonribosomal peptide synthetase |
Adaption, protection |
|
PA4142 |
10.44 |
9.17 |
Secretion protein |
Protein secretion/export apparatus |
|
PA4144 |
5.83 |
7.28 |
opmK |
Hypothetical protein |
Two-component system/ beta-Lactam resistance/Protein secretion/export apparatus |
PA4205 |
23.13 |
98.52 |
mexG |
Hypothetical protein |
Quorum sensing/Membrane protein |
PA4206 |
6.64 |
99.14 |
mexH |
Resistance-nodulation-cell division (RND) efflux membrane fusion protein |
Quorum sensing/Transport of small molecules |
PA4207 |
37.76 |
77.27 |
mexI |
Resistance-nodulation-cell division (RND) efflux transporter |
Quorum sensing/Membrane protein/Transport of small molecules |
PA4208 |
15.76 |
38.10 |
opmD |
Hypothetical protein |
Quorum sensing/Membrane protein/Transport of small molecules |
PA4468 |
5.89 |
6.55 |
sodM |
Superoxide dismutase |
Superoxide radicals degradation/Adaptation, protection |
PA4470 |
6.54 |
6.82 |
fumC1 |
Fumarate hydratase |
TCA cycle/Energy metabolism |
PA4471 |
5.09 |
5.72 |
fagA |
Hypothetical protein |
Hypothetical, unclassified, unknown |
PA4525 |
125.07 |
∞ |
pilA |
Type 4 fimbrial protein |
Two-component system/Pilin biosynthesis/Motility & Attachment |
PA4590 |
8.23 |
11.04 |
Pra |
Protein activator |
Transport of small molecule/Carbon compound catabolism |
PA5180 |
4.06 |
6.26 |
fdhD |
Hypothetical protein |
Hypothetical, unclassified, unknown |
PA5181 |
11.63 |
19.35 |
Oxidoreductase |
Putative enzymes |
|
PA5415 |
4.5 |
3.3 |
glyA1 |
|
Serine hydroxymethyltransferase |