Table 1: Review of published cases of facial infiltrating lipomatosis.

 

Author

Year

Gender

Age

Clinical Features

Recurrence

Slavin, et al. [19]

1983

M

2

Unilateral diffuse soft mass over parotid region.

Yes

F

9

Unilateral swelling of soft tissue extending from cheek up to the temporal region with hypertrophy of underlying zygoma.

No

F

2

Unilateral diffuse mass over anterior maxilla extending to the lower lip, periorbital and frontal regions.

Yes

De Rosa, et al. [27]

1987

M

53

Unilateral hypertrophy of soft tissues of cheek and underlying bone.

Yes

 

F

9

Unilateral hypertrophy of soft tissues of cheek.

Yes

 

F

23

Unilateral hypertrophy of soft tissue in submandibular region, floor of mouth, lower lip and underlying mandibular bone.

yes

MacMillan, et al. [23]

 

1990

F

36

Unilateral diffuse swelling with hypertrophy of soft tissues and underlying bone in the cheek and hypertrophy of soft tissue in the affected side on the palate. Macrodontia of maxillary teeth noted.

Yes

Donati, et al. [3]

1990

M

< 1

Unilateral hypertrophy of soft tissues of the cheek and underlying bone.

No

Patel and Gondalino, et al. [4]

1991

F

< 1

Not known.

Not known

Kang, et al. [5]

1998

M

25

Unilateral hypertrophy of soft tissue and hard tissues of cheek and macrodontia on the affected side.

No

Van Wingerden, et al. [32]

1998

M

< 2

Not Known

Not known

Görken et al.

 

1999

F

6

Unilateral hypertrophy of soft tissues and bone in the anterior maxillary region with multiple, pigmented epithelial polyps and sebaceous nevi.

No

Bouletreau et al. [8]

 

2000

F

16

Unilateral hypertrophy of soft tissue and hard tissues of cheek with macrodontia on affected side.

No

Padwa and Mulliken, et al. [20]

2001

M (8)

F (5)

N = 13

Average = 12.4

Range 1.1 to 22.9

Unilateral hypertrophy of cheek (12) and chin (1) with underlying fat infiltration and skeletal overgrowth (9) Cutaneous capillary blush (9)
Ipsilateral macroglossia (8)
Mucosal neuromas (6)
Early eruption of ipsilateral dentition (12)

Yes-6

No-7

Ergün, et al.

 

2001

M

6

Unilateral hypertrophy of cheek and ipsilateral upper lip.

No

M

45

Unilateral hypertrophy of submental and submandibular tissues including ipsilateral cortical expansion of mandible.

No

Chen, et al.

2002

F

< 1

Unilateral hypertrophy of cheek and ipsilateral upper lip.

NO

Unal, et al.

2003

F

2

Unilateral diffuse soft mass on cheek.

No

Pires Fraga, et al.

2008

M

2

Unilateral diffuse soft tissue swelling on the lower medium-third of the hemi-face extending to oral cavity.

Yes

Kamal, et al. [12]

 

2010

F

16

Unilateral soft diffuse mass in the cheek extending from lower border of mandible, to the inferior orbital rim, to the oral commissure. Hemi mandibular hypertrophy, acceleration of dentoskeletal growth, macrodontia and hypertrophy of the zygomatic bone.

Not known

F

18

Unilateral mass on the left side of the face extending up to the temporal area associated with the hypertrophy of the underlying zygoma.

Not known

M

2

Unilateral diffuse soft mass located on anterior maxilla extending to the inferior orbital rim, lower border of mandible and parotid gland region. Unilateral macrodontia.

Not known

Kim, et al. [25]

2010

F

3.5

Unilateral swelling of cheek, tongue, teeth, mandible, parotid and submandibular salivary glands. Premature eruption of secondary dentition, hyperplastic papillae of the anterior third of tongue and mucosal neuromas.

Yes

Singh Karan, et al. [13]

2011

F

27

Recurrent unilateral facial swelling with history of two previous resections.

No

Tracy, et al. [28]

2013

F

15

Facial asymmetry with significant left facial hypertrophy and swelling associated with facial itching and flushing intermittently.

No