Table 4: Associated factors with mortality in Kairouan, Tunisia, in 2020.
|
Survivors (n = 57) |
Deceased (n = 8) |
|
|||
|
Sociodemographic characteristics &methanol consumption n (%) |
n (%) |
|
|||
|
Educational level |
Analphabet |
3 (5.3) |
0 (0) |
0.480 |
|
|
|
Primary |
48 (84.2) |
8 (100) |
||
|
|
Secondary |
6 (10.5) |
0 (0) |
||
|
Alcohol addiction |
34 (59.6) |
8 (100) |
0.040 |
||
|
Profession |
Unemployed |
52 (91.2) |
8 (100) |
0.380 0.507 |
|
|
Laborer |
5 (8.8) |
0 (0) |
|||
|
Co-ingestion of substance |
20 (35.1) |
7 (87.5) |
0.015 |
||
|
Co-ingestion of Cannabis |
3 (5.3) |
7 (87.5) |
< 10-3 |
||
|
Co-ingestion of Ethanol |
16 (28.1) |
0 (0) |
0.089 |
||
|
|
Median [Q25-Q75] |
Median [Q25-Q75] |
|
||
|
Age (year) |
27.0 [21.0-33.5] |
35.0 [29.7-51.0] |
0.040 |
||
|
Amount of methanol ingested (ml) |
1000.0 [500.0-1500.0] |
1750.0 [1500.0-2000.0] |
< 10-3 |
||
|
Amount of water diluting methanol |
1000.0 [1000.0-2000.0] |
1750.0 [1500.0-2000.0] |
< 10-3 |
||
|
Consultation delay (h) |
48.0 [24.0-50.0] |
24.0 [24.0-24.0] |
< 10-3 |
||
|
Symptoms |
n (%) |
n (%) |
|
||
|
Headache |
54 (94.7) |
3 (37.5) |
< 10-3 |
||
|
Dizziness |
53 (93.0) |
3 (37.5) |
< 10-3 |
||
|
Dyspnea |
3 (5.3) |
1 (12.5) |
0.417 |
||
|
Coma |
2 (3.5) |
5 (62.5) |
< 10-3 |
||
|
Sleepiness |
7 (12.3) |
2 (25.0) |
0.305 |
||
|
Isoreactive mydriasis |
1 (1.8) |
2 (25.0) |
0.04 |
||
|
areactive mydriasis |
0 (0) |
3 (37.5) |
< 10-3 |
||
|
Seizures |
2 (3.5) |
6 (75.0) |
< 10-3 |
||
|
Signs of shock |
2 (3.5) |
7 (87.5) |
< 10-3 |
||
|
|
Median [Q25-Q75] |
Median [Q25-Q75] |
< 10-3 |
||
|
SBP (mmhg) |
120.0 [110.0-130.0] |
90.0 [80.0-112.0] |
< 10-3 |
||
|
DBP (mmhg) |
70.0 [60.0-80.0] |
50.0 [40.0-70.0] |
< 10-3 |
||
|
HR (bpm) |
90.0 [80.0-100.0] |
115.0 [110.0-120.0] |
< 10-3 |
||
|
RR(cpm) |
18.0 [18.0-21.0] |
26.0 [22.0-28.0] |
< 10-3 |
||
|
SaO2 (%) |
98.0 [97.0-99.0] |
93.0 [90.0-95.7] |
0.938 |
||
|
Blood test |
Median [Q25-Q75] |
Median [Q25-Q75] |
|
||
|
Sodium (mmol/L) |
142.0 [140.0-144.0] |
145.0 [143.0-146.0] |
0.025 |
||
|
Potassium (mmol/L) |
3.4.0 [3.0-3.9] |
2.4 [1.8-3.4] |
< 10-3 |
||
|
Hematocrit |
43.0 [39.5-46.0] |
50.0 [44.5-50.7] |
0.044 |
||
|
Blood sugar (mmol/l) |
6.0 [5.5-6.4] |
8.0 [7.0-10.5] |
< 10-3 |
||
|
Creat (mmol/l) |
74.0 [61.5-89.5] |
167.5 [134.0-205.0] |
< 10-3 |
||
|
Urea (mmol/l) |
4.0 [3.1-4.4] |
6.7 [3.7-16.0] |
0.150 |
||
|
PH |
7.3 [7.2-7.4] |
7.0.0 [6.8-7.3] |
0.024 |
||
|
Bicarbonate (mmol/L) |
13.0 [8.0-21.0] |
4.0 [2.6-11.7] |
0.007 |
||
|
PaCO2 (mmHg) |
27.0 [22.0-35.0] |
22.5 [16.5-33.2] |
0.344 |
||
|
PaO2 (mmHg) |
100.0 [80.0-125.5] |
120.0 [105.0-197.5] |
0.35 |
||
|
APACHII Score |
1.0 [0.0-5.0] |
23.0 [15.5-27.0] |
< 10-3 |
||
|
Anion gap (mmol/l) |
31.0 [28.0-40.5] |
36.0 [36.0-36.0] |
0.018 |
||
|
Plasma osmolarity (mosmol/kg) |
289.0 [285.5-292.5] |
306.5 [314.0-301.0] |
< 10-3 |
||
|
|
n (%) |
n (%) |
|
||
|
Dose of methanolemia > 0.5 g/l |
3 (5.3) |
8 (100) |
< 10-3 |
||
|
Toxic optic neuritis |
3 (5.3) |
1 (12.3) |
0.417 |
||
|
Toxic encephalopathy |
2 (3.5) |
2 (25.0) |
0.071 |
||