Table 1: Clinical and morphologic features of prostate carcinoma with prognostic value in cases of prostatic acinar adenocarcinoma Gleason 7 stratified by 3+4 or 4+3 sum.

Table 1: Clinical and morphologic features of prostate carcinoma with prognostic value in cases of prostatic acinar adenocarcinoma Gleason 7 stratified by 3+4 or 4+3 sum. Specimens were processed by complete embedding and evaluated by the original point-count method (n=48).

	Gleason 7 (3+4) n/N (%)	Gleason 7 (4+3) n/N (%)	p value
Preoperative serum PSA
≤ 4,00ng/ml	0	0	0.06
> 4,00 and ≤ 9,99ng/ml	5/7 (71)	2/7 (29)
> 9,99ng/ml	2/7 (29)	5/7 (71)
Percentage of gland involvement by carcinoma
≤ 10%	2/11 (18)	0	0.03
> 10% and ≤ 20%	5/11 (46)	2/9 (22)
> 20% and ≤ 30%	2/11 (18)	3/9 (33)
> 30% and ≤ 40%	2/11 (18)	3/9 (33)
> 60% and ≤ 80%	0	1/9 (11)
Positive circumferential surgical margin	4/11 (36)	4/9 (44)	1.00
Positive basal surgical margin	0	4/9 (44)	0.03
Positive apical surgical margin	3/11 (27)	0	0.22
Extraprostatic extension	2/11 (18)	5/9 (56)	0.15
Seminal vesicle invasion	1/11 (9)	4/9 (44)	0.12
Ki-67 immunostaining (% of cancer cells)
Negative	2/11 (18)	0	0.04
> 0% and ≤ 3,0%	9/11(82)	7/9 (78)
> 3,0%		2/9 (22)