Table 2: Clinical and morphologic features of prostate carcinoma with prognostic value in cases of prostatic acinar adenocarcinoma Gleason 7 stratified by 3+4 or 4+3 sum. Specimens were processed by partial embedding and evaluated by the adapted point-count method (n=106).

Gleason 7 (3+4) mean ± SD or n/N (%) Gleason 7 (4+3) mean ± SD or n/N (%) p value
Age (years) 64.3 ± 6.7 62.9 ± 10.6 0.38
Preoperative serum PSA 11.0 ± 3.3 11.8 ± 6.05 0.01
≤ 4,00ng/ml 01/39 (03) 01/16 (06) 0.04
> 4,00 and ≤ 9,99ng/ml 28/39 (72) 05/16 (32)
> 9,99ng/ml 10/39 (26) 10/16 (62)
Percentage of gland involvement by carcinoma 16 ± 11.4 19 ± 11.7 0.29
≤ 10% 27/76 (23) 07/30 (35) 0.14
> 10% and ≤ 20% 22/76 (29) 09/30 (30)
> 20% and ≤ 30% 20/76 (26) 07/30 (23)
> 30% and ≤ 40% 03/76 (04) 06/30 (20)
> 60% and ≤ 80% 07/76 (05) 01/30 (03)
Tumor volume (ml) 12.0 ± 3.48 12.0 ± 3.47 0.6
Positive circumferential surgical margin 18/76 (23) 09/30 (30) 0.3
Positive basal surgical margin 04/76 (05) 03/30 (10) 0.3
Positive apical surgical margin 02/76 (03) 02/30 (07) 0.3
Extraprostatic extension 15/76 (20) 11/30 (38) 0.04
Seminal vesicle invasion 03/76 (04) 05/30 (17) 0.02
Tertiary Gleason 5 07/76 (09) 02/30 (07) 0.8