Table 1: Demographic, intraoperative, and laboratory data.

Variables Early-weaning outcomes P-value Late-weaning outcomes P-value
SIMPLE (n = 101) DIFFICUL (n = 25) PROLON (n = 8) None (n = 126) REINTUBATIO (n = 6)
Age (Y) 58 (56-60) 54 (47-60) 72 (68-76) 0.001*, 57.3 (55-59.5) 66.3 (60.4-72.3) 0.029*
Male (n) 72 (71%) 18 (72%) 4 (50%) 0.437 90 (72%) 3 (50%) 0.234
BMI 24.2 (23-24.8) 24.3 (22.1-26.7) 24.6 (17.9-31.3) 0.946 23.9 (23-24.6) 27.6 (22.8-32.4) 0.030*
COPD (n) 6 (5.9%) 1 (4.0%) 0 (0%) 0.584 7 (5.6%) 0 (0%) 0.551
Pre-O2 Sat (%) 97.37 (95.6-99.1) 97.94 (96.9-98.9) 97.3 (96.4-98.2) 0.984 97.5 (96-98.9) 96.6 (95.1-97.9) 0.769
Pre-hct (%) 39.5 (38-40.1) 40.4 (37.0-43.1) 34.3 (31.5-37.1) 0.038*, 39.6 (38-40.7) 36.5 (32.2-40.8) 0.214
Pre-WBC 7.5 (6.7-8.3) 7.5 (6.5-8.5) 7.5 (3.4-11.7) 0.999 7.1 (6.7-7.5) 14.1 (2.9-25.3) 0.001*
Pre-GFR 87.6 (84-91.3) 88.3 (75.4-101.1) 57.9 (42.3-73.6) 0.001*, 87.6 (84-91.5) 66.1 (51.5-80.9) 0.034*
LVEF (%) 58.5 (56-61.1) 58.6 (52.9-64.4) 52.7 (55.8-60.4) 0.505 58.2 (56-60.6) 57.8 (43.2-72.4) 0.943
Operation Type (n) 0.090 0.644
CABG 46 7 2 52 2
Valve 34 7 3 40 3
Aneurysm 9 3 1 13 0
Congenital 2 4 0 6 0
Combined 10 4 2 15 1
CPB time (min) 139 (130-147) 139 (123-155) 147 (106-188) 0.872 140 (132-147) 136 (101-172) 0.864
inotrope > 1 (n) 36 (35.6%) 14 (56%) 4 (50%) 0.151 51 (40.8%) 2 (33.3%) 0.535
PRC Volume (ml) 354.8 (308-401) 414.8 (280-550) 502.5 (331-419) 0.208 374.6 (328421) 378.0 (236-520) 0.966
Post-hct (%) 30.8 (29-31.7) 30.4 (28.4-32.4) 27.5 (24.9-30.1) 0.130 30.9 (30-31.7) 24.8 (22.1-27.5) 0.001*
Post-WBC 14.6 (13.-15.9) 15.6 (12.5-18.7) 12.9 (3.9-22.1) 0.644 14.5 (13-15.6) 18.2 (7.9-28.5) 0.187
Post-GFR 95.4 (91-99.4) 96.8 (80.7-112.8) 60.5 (43.5-77.4) 0.001*, 95.5 (91-99.9) 70.8 (55.6-86.0) 0.020*

Notes: Values are mean (95% CI) and number (frequency), BMI: Body Mass Index; Pre (Post)-X: Pre-operative (Postoperative)-X; O2sat = Oxygen saturation at FiO2 = 0.2; hct = Hematocrit, WBC = White blood cell count; CPB time = Duration under cardiopulmonary bypass machine; GFR(ml/min/1.73m2); WBC (cell/mm3/103); BMI (kg/m2); PRC volume = Volume of intraoperative PRC transfusion For ANOVA: * = Significance among 3 groups, = Post hoc significance between SIMPLE-PROLONG and DIFFICULT-PROLONG but without significance between SIMPLE-DIFFICULT.