Table 1: Demographic, intraoperative, and laboratory data.
Variables | Early-weaning outcomes | P-value | Late-weaning outcomes | P-value | |||
SIMPLE (n = 101) | DIFFICUL (n = 25) | PROLON (n = 8) | None (n = 126) | REINTUBATIO (n = 6) | |||
Age (Y) | 58 (56-60) | 54 (47-60) | 72 (68-76) | 0.001*,† | 57.3 (55-59.5) | 66.3 (60.4-72.3) | 0.029* |
Male (n) | 72 (71%) | 18 (72%) | 4 (50%) | 0.437 | 90 (72%) | 3 (50%) | 0.234 |
BMI | 24.2 (23-24.8) | 24.3 (22.1-26.7) | 24.6 (17.9-31.3) | 0.946 | 23.9 (23-24.6) | 27.6 (22.8-32.4) | 0.030* |
COPD (n) | 6 (5.9%) | 1 (4.0%) | 0 (0%) | 0.584 | 7 (5.6%) | 0 (0%) | 0.551 |
Pre-O2 Sat (%) | 97.37 (95.6-99.1) | 97.94 (96.9-98.9) | 97.3 (96.4-98.2) | 0.984 | 97.5 (96-98.9) | 96.6 (95.1-97.9) | 0.769 |
Pre-hct (%) | 39.5 (38-40.1) | 40.4 (37.0-43.1) | 34.3 (31.5-37.1) | 0.038*,† | 39.6 (38-40.7) | 36.5 (32.2-40.8) | 0.214 |
Pre-WBC | 7.5 (6.7-8.3) | 7.5 (6.5-8.5) | 7.5 (3.4-11.7) | 0.999 | 7.1 (6.7-7.5) | 14.1 (2.9-25.3) | 0.001* |
Pre-GFR | 87.6 (84-91.3) | 88.3 (75.4-101.1) | 57.9 (42.3-73.6) | 0.001*,† | 87.6 (84-91.5) | 66.1 (51.5-80.9) | 0.034* |
LVEF (%) | 58.5 (56-61.1) | 58.6 (52.9-64.4) | 52.7 (55.8-60.4) | 0.505 | 58.2 (56-60.6) | 57.8 (43.2-72.4) | 0.943 |
Operation Type (n) | 0.090 | 0.644 | |||||
CABG | 46 | 7 | 2 | 52 | 2 | ||
Valve | 34 | 7 | 3 | 40 | 3 | ||
Aneurysm | 9 | 3 | 1 | 13 | 0 | ||
Congenital | 2 | 4 | 0 | 6 | 0 | ||
Combined | 10 | 4 | 2 | 15 | 1 | ||
CPB time (min) | 139 (130-147) | 139 (123-155) | 147 (106-188) | 0.872 | 140 (132-147) | 136 (101-172) | 0.864 |
inotrope > 1 (n) | 36 (35.6%) | 14 (56%) | 4 (50%) | 0.151 | 51 (40.8%) | 2 (33.3%) | 0.535 |
PRC Volume (ml) | 354.8 (308-401) | 414.8 (280-550) | 502.5 (331-419) | 0.208 | 374.6 (328421) | 378.0 (236-520) | 0.966 |
Post-hct (%) | 30.8 (29-31.7) | 30.4 (28.4-32.4) | 27.5 (24.9-30.1) | 0.130 | 30.9 (30-31.7) | 24.8 (22.1-27.5) | 0.001* |
Post-WBC | 14.6 (13.-15.9) | 15.6 (12.5-18.7) | 12.9 (3.9-22.1) | 0.644 | 14.5 (13-15.6) | 18.2 (7.9-28.5) | 0.187 |
Post-GFR | 95.4 (91-99.4) | 96.8 (80.7-112.8) | 60.5 (43.5-77.4) | 0.001*,† | 95.5 (91-99.9) | 70.8 (55.6-86.0) | 0.020* |
Notes: Values are mean (95% CI) and number (frequency), BMI: Body Mass Index; Pre (Post)-X: Pre-operative (Postoperative)-X; O2sat = Oxygen saturation at FiO2 = 0.2; hct = Hematocrit, WBC = White blood cell count; CPB time = Duration under cardiopulmonary bypass machine; GFR(ml/min/1.73m2); WBC (cell/mm3/103); BMI (kg/m2); PRC volume = Volume of intraoperative PRC transfusion For ANOVA: * = Significance among 3 groups, † = Post hoc significance between SIMPLE-PROLONG and DIFFICULT-PROLONG but without significance between SIMPLE-DIFFICULT.