Table 2: Classification of thrombocytopenia's etiology according to the trimester PLT count. Others include: Bone marrow failure, antiphospholipid antibody syndrome, autoimmune conditions.
Etiology of thrombocytopenia according to the trimester and PLT count |
||
First Trimester |
Second Trimester |
Third Trimester |
Immune thrombocytopenia (ITP) |
PLT > 100,000 μL |
PLT > 100,000 μL |
Hereditary thrombocytopenia (HT) |
Gestational thrombocytopenia |
Gestational thrombocytopenia |
Others |
ITP |
Pre-eclampia/HELLP |
Thrombotic microangiopathy (TMA) |
Pre-eclampia/HELLP |
Others/TMA/ITP/HT |
|
HT/Others/TMA |
|
|
PLT < 100,000 μL |
PLT < 50,000 μL |
|
ITP |
Pre-eclampia/HELLP |
|
HT |
ITP |
|
Pre-eclampia/HELLP |
Others |
|
Others |
TMA |
|
Gestational thrombocytopenia |
Gestational thrombocytopenia/HT |
|
TMA |
|