Table 4: MiRNAs deregulated in astrocytomas
AA: Anaplastic Astrocytomas, GBM: Glioblastoma, qRT-PCR: quantitative Real-Time Polymerase Chain Reaction, NGS: Next Generation Sequencing.

miRNA up-regulated	miRNA down-regulated	Samples Setting	Methods	References
-21	None Found	Astrocytoma vs Normal Brain	Microarray	[43]
-21, -221	-181b	AA vs Normal Brain	qRT-PCR	[25]
-21, -24	-181b, -124, -125, -106a	AA vs Normal Adjacent Tissue	qRT-PCR	[53]
-21	-106a, -181b	Correlated with poor survival		[53]
-9, -15a, -17, -19a, -20a, -21, -25, -28, -130b, -140, -210	-184, -328	Astrocytoma Correlated to progression to GBM	qRT-PCR	[134]
	-15b*, -23a, -133a, -150*, -197, -497, -548b-5p	Serum vs Normal Controls	NGS and qRT-PCR	[52]
	-23a, -150*, -197, -548b-5p	Serum vs Astrogliosis		[52]