Mann-Kendall Trend test statistics evaluating the presence of trends in breath acetone and symptom burden across time for each participant throughout the study.

Table 2: Mann-Kendall Trend test statistics evaluating the presence of trends in breath acetone and symptom burden across time for each participant throughout the study.

Breath Acetone

Symptom Severity

Symptom Number

Participant 1

0.048^a

1.00^b

0.335^c

-0.920^a

0.000^b

-3.000^c

-0.908^a

0.000^b

-2.000^c

Participant 2

-0.303^a

0.197^b

-0.228^c

-0.824^a

< 0.0001^b

-2.846^c

-0.703^a

0.001^b

-1.429^c

Participant 3

-0.159^a

0.528^b

-0.250^c

-0.922^a

< 0.0001^b

-2.333^c

-0.913^a

< 0.0001^b

-1.775^c

Participant 4

-0.478^a

0.018^b

-0.926^c

-0.394^a

0.042^b

-1.600^c

-0.362^a

0.083^b

-0.143^c

Participant 5

-0.141^a

0.600^b

-0.091^c

-0.699^a

0.008^b

-0.333^c

-0.669^a

0.008^b

-0.333^c

Participant 6

-0.278^a

0.358^b

-1.433^c

-0.932^a

0.000^b

-1.000^c

-0.908^a

0.000^b

-0.800^c