Table 2: Initial clinical presentation and lab results vs. flow cytometry.
|
Variable number (%) |
Diagnosis |
|
|
|
|
|
B-ALL |
T-ALL |
Burkitt-ALL |
Others |
|
Symptoms and sings 43 (84%) |
|
|
|
|
|
Fatigue |
17 (65%) |
7 (54%) |
1 (50%) |
1 (50%) |
|
Fever |
14 (54%) |
7 (54%) |
1 (50%) |
0 (0%) |
|
Night sweat |
8 (31%) |
7 (54%) |
1 (50%) |
1 (50%) |
|
Bone pain |
11 (42%) |
5 (38%) |
1 (50%) |
1 (50%) |
|
Anorexia |
8 (31%) |
6 (46%) |
2 (100%) |
0 (0%) |
|
Respiratory tract infection |
10 (38%) |
4 (31%) |
0 (0%) |
0 (0%) |
|
Weight loss |
11 (42%) |
4 (31%) |
1 (50%) |
0 (0%) |
|
Shortness of breath |
8 (31%) |
4 (31%) |
0 (0%) |
0 (0%) |
|
Abdominal pain |
3 (12%) |
4 (31%) |
2 (100%) |
1 (50%) |
|
Lymphadenopathy |
4 (15%) |
5 (38%) |
1 (50%) |
1 (50%) |
|
Epistaxis |
5 (19%) |
3 (23%) |
2 (100%) |
1 (50%) |
|
Pallor |
7 (27%) |
0 (0%) |
0 (0%) |
0 (0%) |
|
Headache |
8 (31%) |
0 (0%) |
0 (0%) |
0 (0%) |
|
Bruising |
5 (19%) |
2 (15%) |
1 (50%) |
0 (0%) |
|
Dizziness |
5 (19%) |
1 (8%) |
0 (0%) |
0 (0%) |
|
CNS involvment |
2 (8%) |
0 (0%) |
1 (50%) |
0 (0%) |
|
Labs |
|
|
|
|
|
WBC count 42(82%) |
|
|
|
|
|
Mean × 109/L(SD) |
22.28 (34.5) |
41.71 (43.4) |
14.85 (19.3) |
39.75 (35.5) |
|
Median × 109/L(IQR) |
6.3 (28.7) |
21.6 (45.7) |
14.85 |
39.75 |
|
Hb count 43 (84%) |
|
|
|
|
|
Mean g/dl (SD) |
9.2 (1.94) |
10.8 (2.74) |
8.7 (1.84) |
10.05 (2.1) |
|
Median g/sd(IQR) |
8.9 (3.3) |
10.4 (2.4) |
8.7 |
10.05 |
|
Platelets count 43 (84%) |
|
|
|
|
|
Mean × 109/L(SD) |
67.98 (79.3) |
129.78 (156.2) |
23 (4.2) |
57.5 (34.6) |
|
Median × 109/L(IQR) |
31 (85) |
48 (271.3) |
23 |
57.5 |
Others: T-ALL/B-ALL lineage and T-ALL/myeloid lineage; Fever: Temperature > 37.5 orally; Respiratory tract infection: Recurrent upper RTI or lower RTI not responding to conventional treatment; Weight loss: Unintentional documented loss > 5% of total body weight in 6 months; CNS involvement: Based on spinal cytology or documented metastasis on imaging; WBC: White blood cells; Hb: Hemoglobin