Table 1: Laboratory results during clinical investigation.
| 
				 Laboratory tests  | 
			
				 Previous tests  | 
			
				 Tests requested by the haematologist  | 
		|||
| 
				 D – 104  | 
			
				 D – 29  | 
			
				 D – 7  | 
			
				 D + 8  | 
			
				 D + 435  | 
		|
| 
				 Hemogram  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
		
| 
				 Hemoglobin (g/dL)  | 
			
				 13,3  | 
			
				 13,0  | 
			
				 11,6  | 
			
				 12,3  | 
			
				 13,6  | 
		
| 
				 Hematocrit (%)  | 
			
				 38,9  | 
			
				 39,8  | 
			
				 34,2  | 
			
				 36,6  | 
			
				 40,0  | 
		
| 
				 MCV (µms³)  | 
			
				 86,4  | 
			
				 87,1  | 
			
				 89,1  | 
			
				 90,4  | 
			
				 86,0  | 
		
| 
				 Leukocytes (/mm³)  | 
			
				 6.050  | 
			
				 6.870  | 
			
				 7.900  | 
			
				 4.910  | 
			
				 6.660  | 
		
| 
				 - Segmented neutrophils (%)  | 
			
				 40,6  | 
			
				 45,5  | 
			
				 55,3  | 
			
				 44,8  | 
			
				 44,0  | 
		
| 
				 - Band forms (%)  | 
			
				 2,1  | 
			
				 1,2  | 
			
				 1,0  | 
			
				 1,2  | 
			
				 1,0  | 
		
| 
				 - Eosinophils (%)  | 
			
				 1,5  | 
			
				 1,9  | 
			
				 2,5  | 
			
				 2,0  | 
			
				 1,0  | 
		
| 
				 -Lymphocytes (%)  | 
			
				 48,2  | 
			
				 44,2  | 
			
				 32,2  | 
			
				 43,6  | 
			
				 48,0  | 
		
| 
				 - Monocytes (%)  | 
			
				 7,6  | 
			
				 7,2  | 
			
				 9,0  | 
			
				 8,4  | 
			
				 6,0  | 
		
| 
				 Platelets (/mm³)  | 
			
				 238.000  | 
			
				 208.000  | 
			
				 364.000  | 
			
				 285.000  | 
			
				 226.400  | 
		
| 
				 Coagulogram  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
		
| 
				 PT (INR - seconds)  | 
			
				 1,08  | 
			
				 -  | 
			
				 -  | 
			
				 1,13  | 
			
				 1,00  | 
		
| 
				 aPTT (seconds)  | 
			
				 28,0  | 
			
				 -  | 
			
				 -  | 
			
				 32,5  | 
			
				 28,0  | 
		
| 
				 TT (seconds)  | 
			
				 
  | 
			
				 -  | 
			
				 -  | 
			
				 10,3  | 
			
				 -  | 
		
| 
				 Factor VIII (%)  | 
			
				 
  | 
			
				 -  | 
			
				 -  | 
			
				 111  | 
			
				 -  | 
		
| 
				 Factor IX (%)  | 
			
				 
  | 
			
				 -  | 
			
				 -  | 
			
				 104  | 
			
				 -  | 
		
| 
				 Fibrinogen (mg/dL)  | 
			
				 
  | 
			
				 -  | 
			
				 -  | 
			
				 354,0  | 
			
				 -  | 
		
| 
				 Ristocetin Cofactor Activity (%)  | 
			
				 
  | 
			
				 -  | 
			
				 -  | 
			
				 120,7  | 
			
				 -  | 
		
| 
				 Von Willebrand Antigen (%)  | 
			
				 
  | 
			
				 -  | 
			
				 -  | 
			
				 130  | 
			
				 -  | 
		
| 
				 Lipid profile and blood glucose  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
		
| 
				 Total cholesterol (mg/dL)  | 
			
				 -  | 
			
				 221  | 
			
				 -  | 
			
				 -  | 
			
				 211  | 
		
| 
				 HDL (mg/dL)  | 
			
				 -  | 
			
				 46  | 
			
				 -  | 
			
				 -  | 
			
				 56  | 
		
| 
				 Triglycerides (mg/dL)  | 
			
				 -  | 
			
				 100  | 
			
				 -  | 
			
				 -  | 
			
				 112  | 
		
| 
				 Fasting blood glucose (mg/dL)  | 
			
				 80  | 
			
				 70  | 
			
				 -  | 
			
				 -  | 
			
				 78  | 
		
| 
				 Serum iron profile  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
		
| 
				 Serum iron (µg/dL)  | 
			
				 -  | 
			
				 128  | 
			
				 -  | 
			
				 83  | 
			
				 89  | 
		
| 
				 Ferritin (ng/mL)  | 
			
				 -  | 
			
				 75,2  | 
			
				 -  | 
			
				 86,9  | 
			
				 29,1  | 
		
| 
				 Transferrin saturation (%)  | 
			
				 -  | 
			
				 42  | 
			
				 -  | 
			
				 26  | 
			
				 -  | 
		
| 
				 Total iron binding capacity (µg/dL)  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
			
				 313  | 
			
				 -  | 
		
| 
				 Hormonal profile  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
		
| 
				 Beta-hCG (mUI/mL)  | 
			
				 Negative  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
		
| 
				 TSH (µUI/mL)  | 
			
				 -  | 
			
				 2,62  | 
			
				 -  | 
			
				 -  | 
			
				 1,88  | 
		
| 
				 Free T4 (ng/dL)  | 
			
				 -  | 
			
				 7,4  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
		
| 
				 Hepatic profile  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
		
| 
				 AST (U/L)  | 
			
				 -  | 
			
				 20  | 
			
				 -  | 
			
				 -  | 
			
				 15  | 
		
| 
				 ALT (U/L)  | 
			
				 -  | 
			
				 12  | 
			
				 -  | 
			
				 -  | 
			
				 13  | 
		
| 
				 Direct bilirubin (mg/dL)  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
			
				 0,14  | 
		
| 
				 Indirect bilirubin (mg/dL)  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
			
				 0,26  | 
		
| 
				 Kidney function  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
		
| 
				 Creatinin (mg/dL)  | 
			
				 0,91  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
			
				 0,76  | 
		
| 
				 Others  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
			
				 
  | 
		
| 
				 Folic acid (ng/mL)  | 
			
				 -  | 
			
				 6,01  | 
			
				 -  | 
			
				 -  | 
			
				 -  | 
		
| 
				 Vitamin D (ng/mL)  | 
			
				 -  | 
			
				 42,9  | 
			
				 -  | 
			
				 -  | 
			
				 24,1  | 
		
| 
				 Vitamin B12 (pg/ml)  | 
			
				 -  | 
			
				 387  | 
			
				 -  | 
			
				 -  | 
			
				 351  | 
		
Legend: D: days relative to the first hematological consultation. MCV: mean corpuscular volume. PT: prothrombin time. INR: international normalized ratio. aPTT: activated partial thromboplastin time. TT: thrombin time. HDL: high-density lipoprotein. TIBC: total iron-binding capacity. HCG: human chorionic gonadotropin. TSH: thyroid-stimulating hormone. AST: aspartate aminotransferase. ALT: alanine aminotransferase