Table 1: Serum GGT, ALT, AST activities, levels of TP and ALB in sickle cell anaemic patients and controls in the study.

Parameters

Patients

n = 50

Controls

n = 50

t-value

p-value

GCT

28.31 ± 12.68 U/L

23.27 ± 6.95 U/L

2.5

< 0.05 (S)

ALT

29.64 ± 13.32 U/L

24.12 ± 9.66 U/L

2.4

< 0.05 (S)

AST

42.14 ± 25.10 U/L

21.30 ± 6.73 U/L

5.7

< 0.05 (S)

TP

6.18 ± 1.27 g/dL

7.58 ± 1.34 g/dL

5.4

< 0.05 (S)

ALB

4.28 ± 0.82 g/dL

5.27 ± 0.92 g/dL

6.0

< 0.05 (S)

df = 98; p < 0.05

This table shows the serum GGT, ALT and AST activities of patients with sickle cell anaemia as significantly higher (p < 0.05) while the levels of total protein and albumin of patients with sickle cell anaemia were significantly low (p < 0.05) when compared with the control subjects.