Table 3: SNPs within the PTPRN2 gene associated with AAO of cancer using PROC PHREG (p < 0.05)

 

SNP

Positiona

Alleleb

GTc

HRd

pe

AICf

HRg

DICh

rs13239831

157124954

T

C-C

0.66(0.48-0.91)

1.16E-02

7914.6

0.68(0.48-0.9)

7914.5

rs7783909

157287177

A

A-A

1.67(1.11-2.5)

1.36E-02

7954.4

1.67(1.03-2.36)

7954.3

rs6942917

157385952

A

A-G

1.27(1.07-1.51)

6.4E-03

7952.6

1.27(1.06-1.49)

7952.6

rs4716881

157509808

A

A-A

1.32(1.03-1.71)

3.03E-02

7954.0

1.33(1.0-1.66)

7953.9

rs4716535

157516571

T

C_T

1.23(1.05-1.44)

1.08E-02

7952.8

1.0(0.7-1.3)

7952.8

rs9654713

157607912

A

A_G

1.23(1.06-1.44)

8.4E-03

7953.1

1.24(1.06-1.44)

7953.1

rs4909140

157721662

G

G_G

1.38(1.11-1.71)

3.3E-03

7951.4

1.39(1.1-1.69)

7951.4

rs7777448

157724510

A

A_A

1.36(1.04-1.63)

2.35E-02

7902.7

1.3(1.01-1.6)

7902.7

rs7777968

157773101

G

A_G

1.55(1.08-2.24)

1.88E-02

7953.8

1.6(1.04-2.22)

7953.8

rs1670356

157953979

A

A‑C

0.83(0.71-0.97)

1.75E-02

7940.7

0.83(0.7-0.96)

7940.7

rs1670340

157963783

C

C_C

1.28(1.04-1.58)

2.19E-02

7954.8

1.29(1.03-1.56)

7954.7

 

 a Physical position(bp); b Minor allele; c Tested Genotype comparing with the reference;

 d Hazards ratio for the tested genotype based on classic Cox regression analysis using PROC PHREG;

 e p-value for the tested genotype based on classic Cox regression analysis;

 f Akaike information criterion (AIC) value based on classic Cox regression analysis;      

 g Hazards ratio for the tested genotype based on Bayesian Cox regression analysis;

 h Deviance information criteria (DIC) value based on Bayesian Cox regression analysis.