Table 4: N = 120. Designs for testing H0: p p0 vs. H1: p > p0 with = 0: 05 and power at least 80% at p1 = p0 + 0:15. For each setting the Rows 1-3 contain the Types 1-3 two-stage designs. The left and rights parts are for the first type and second type of optimal designs.

p0 (1-stage) 2-stage minimizing EN0 2-stage minimizing n2
Design EN0 n2 P ET0 Design EN0 n2 P ET0


0.1

(29; 5)

(19, 4; 29, 5)

(22, 3; 29, 5)

(20, 3, 4; 29, 5)

28.8

24.7

22.6

29

29

29

0.02

0.62

0.71

(19, 4; 29, 5)

(22, 3; 29, 5)

(20, 3, 4; 29, 5)

28.8

24.7

22.6

29

29

29

0.02

0.62

0.71


0.2

(39; 11)

(35, 10; 38, 11)

(23, 5; 39, 11)

(22, 5, 8; 39, 11)

37.9

31.1

29.7

38

39

39

0.04

0.49

0.55

(35, 10; 38, 11)

(23, 5; 39, 11)

(35, 1, 10; 38, 11)

37.9

31.1

37.9

38

39

38

0.04

0.49

0.04


0.3

(44; 17)

(24, 11; 44, 17)

(26, 9; 42, 16)

(26, 9, 13; 42, 16)

43.6

31.8

31.7

44

42

42

0.01

0.64

0.64

(24, 11; 44, 17)

(24, 8; 42, 16)

(24, 8, 13; 42, 16)

43.6

31.8

31.8

44

42

42

0.01

0.57

0.57


0.4

(45; 22)

(29, 16; 45, 22)

(31, 13; 45, 22)

(30, 13, 17; 45, 22)

42.7

37.7

36

45

45

45

0.02

0.52

0.6

(29, 16; 45, 22)

(31, 13; 45, 22)

(30, 13, 17; 45, 22)

42.7

37.7

36

45

45

45

0.02

0.52

0.6


0.5

(46; 27)

(27, 18; 44, 26)

(24, 13; 46, 27)

(24, 13, 17; 46, 27)

43.8

33

32.9

44

46

46

0.01

0.59

0.6

(22, 16; 44, 26)

(24, 13; 46, 27)

(22, 1, 16; 44, 26)

43.9

33

43.9

44

46

44

0.01

0.59

0.61


0.6

(42; 29)

(29, 22; 42, 29)

(21, 13; 42, 29)

(26, 17, 20; 42, 29)

41.8

32

31.3

42

42

42

0.01

0.48

0.67

(29, 22; 42, 29)

(21, 13; 42, 29)

(26, 17, 20; 42, 29)

41.8

32

31.3

42

42

42

0.01

0.48

0.67


0.7

(38; 30)

(23, 20; 38, 30)

(24, 19; 37, 29)

(22, 17, 19; 38, 30)

37.9

26.6

26.5

38

37

38

0.01

0.8

0.72

(23, 20; 38, 30)

(24, 19; 37, 29)

(24, 19, 22; 37, 29)

37.9

26.6

26.6

38

37

37

0.01

0.8

0.8