Table 3: SNPs associated with the age at onset of AD using PROC PHREG (p < 0.05).

SNP GTa HRb pc AICd HRe HPDf DICg
rs7746856 C-C 7622.19 7622.21
A-A 1.28 (1.04 - 1.57) 0.0208 1.28 1.02 - 1.56
A-G 1.02 (0.87 - 1.20) 0.82 1.02 0.86 - 1.19
rs6941988 T-T 7622.24 7622.32
C-C 1.27 (1.03 - 1.56) 0.026 1.27 1.02 - 1.54
C-T 1.01 (0.85 - 1.18) 0.959 1.01 0.85 - 1.18
rs9499937 C-C 7616.16 7616.17
C-T 1.33 (1.13 - 1.57) 5.0 × 10-4 1.34 1.11 - 1.55
T-T 1.35 (0.80 - 2.27) 0.266 1.35 0.68 - 2.06
rs7770002 A-G 7622.37 7622.34
A-C 1.27 (1.03 - 1.57) 0.0239 1.28 1.02 - 1.55
C-C 1.01 (0.86 - 1.20) 0.864 1.02 0.85 - 1.19

aTested genotype comparing with the reference; bHazards Ratio (HR) for the tested genotype based on classic Cox regression analysis using PROC PHREG; cp-value for the tested genotype based on classic Cox regression analysis; dAkaike Information Criterion (AIC) value based on classic Cox regression analysis; eHR for the tested genotype based on Bayesian Cox regression analysis; fLower and upper 95% Highest Posterior Density (HPD) of HR based on Bayesian Cox regression analysis; gDeviance Information Criteria (DIC) value based on Bayesian Cox regression analysis.