Haplotype analysis of the risk and age at onset of AD in the family sample.

Table 4: Haplotype analysis of the risk and age at onset of AD in the family sample.

	SNPs		Haplotype^a	Frequency^b	Fam#^c	p-value^d
Risk of AD
rs9499927	rs9404573		C-C	0.01	37	0.00144
rs9404573	rs9499934		C-T	0.02	41	0.00355
rs6937432	rs6940552		T-A	0.01	37	0.00097
rs1378720	rs13198196		C-T	0.02	60	0.0147
rs9486015	rs9486018		T-T	0.06	101	0.00156
rs9486018	rs4079063		T-G	0.07	120	0.00446
rs9486015	rs9486018	rs4079063	T-T-G	0.04	54	0.00227
Age at onset of AD
rs6937026	rs4946640		C-C	0.23	166	0.0223
rs6937026	rs4946640	rs6910034	C-A-G	0.51	156	0.0274
			C-C-A	0.16	100	0.0225
rs9486015	rs9486018	rs4079063	T-T-A	0.01	22	0.0719
			T-T-G	0.04	46	0.0487

^aHaplotype inferred from 2 or 3 SNPs; ^bHaplotype frequency; ^cFAM# refers to the number of informative families using an additive model; ^dp-value for the haplotype based on FBAT-GEE analysis for the risk or based on FBAT-Wilcoxon analysis for the age at onset.